(5-(4-Chlorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methanone CAS 1072874-79-3
| CAS No. | 1072874-79-3 |
| Molecular Formula | C23H18ClF3N6O |
| Molecular Weight | 486.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(5-(4-Chlorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methanone (CAS 1072874-79-3), molecular formula C23H18ClF3N6O and molecular weight 486.88 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (5-(4-Chlorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methanone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 486.88 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H18ClF3N6O |
| Molecular Weight | 486.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 6 |
Related Chlorophenyl Standards
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- Methyl 2-(2-(4-chlorophenyl)acetamido)-5-((2-ethoxyphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 335409-31-9)
- Methyl 2-(2-(4-chlorophenyl)acetamido)-5-((4-ethoxyphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 505096-61-7)
- 3-(4-Chlorophenyl)-1-(2-nitro-4-(trifluoromethyl)phenyl)-6-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine (CAS 338770-83-5)
- N-(((4-chlorophenyl)carbamoyl)oxy)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 861208-34-6)
- 4-(4-Chlorophenyl)-1-(4-ethylphenyl)-6-methyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,2,3,4-tetrahydropyrimidine-2-thione (CAS 1169977-10-9)
- 1-(4-Chlorophenyl)-3-{3-[(4-chlorophenyl)sulfanyl]-5-(trifluoromethyl)pyridine-2-carbonyl}urea (CAS 338759-10-7)
Recommended Standards
- 3-Cyano-4-(3-chloro-4-fluoroanilino)-7-ethoxy-6-(phthalimidyl)quinoline 915945-40-3 (CAS 915945-40-3)
- 2-((4-Chloro-N-(3-(trifluoromethyl)phenyl)phenyl)sulfonamido)-N-(2-fluorophenyl)acetamide (CAS 337922-23-3)
- Sofosbuvir Impurity 17 (CAS 1496551-71-3)
- 1-[4-Chloro-3-(trifluoromethyl)phenyl]-3-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]urea (CAS 1796920-11-0)
- Methyl 3-((tert-butoxycarbonyl)amino)-2-oxopropanoate (CAS 436154-66-4)
- 3-(3-Chloro-5-fluorophenyl)propionaldehyde (CAS 951890-33-8)
- 3-(2-Methoxy-4-methylphenyl)azetidin-3-ol (CAS 1388028-46-3)
- 4-Cyclopropoxybenzene-1,2-disulfonamide (CAS 1243464-69-8)
- Dalbavancin Impurity 22 (CAS CATO-C4X-160222)
- 4-Bromo-5-[(4-chlorophenyl)sulfanyl]-2-furaldehyde (CAS 425681-51-2)
- 1-(2,4-Dibromophenyl)-1H-pyrrole-2-carbaldehyde (CAS 299164-67-3)
- 6-Methyl-4,5,6,7-tetrahydro-1,3-benzothiazol-2-amine (CAS 7496-50-6)
- 6-Hydroxy-4-methoxy-7-nitrobenzofuran-5-carboxamide (CAS 88258-45-1)
- Semaglutide impurity 30 (CAS CATO-C4X-222630)
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