Metronidazole EP Impurity E CAS 705-19-1
| CAS No. | 705-19-1 |
| Molecular Formula | C6H9N3O3 |
| Molecular Weight | 171.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Metronidazole EP Impurity E (CAS 705-19-1), a pharmacopoeial impurity reference standard (molecular formula C6H9N3O3, MW 171.15 g/mol) used for the identification and quantification of trace impurities in APIs.
Metronidazole EP Impurity E (C6H9N3O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Metronidazole EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H9N3O3 |
| Molecular Weight | 171.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 3 |
Related Metronidazole Standards
- Metronidazole Impurity 15 (CAS 110578-73-9)
- Metronidazole Impurity 18 (CAS 113385-77-6)
- Metronidazole (CAS 443-48-1)
- Metronidazole Impurity N30 (CAS 56910-52-2)
- Metronidazole-d3 (CAS 83413-09-6)
- Metronidazole-13C2,15N2 (CAS 1173020-03-5)
- Metronidazole-d4 (CAS 1261392-47-5)
- Metronidazole Impurity 27 (CAS 34916-84-2)
Recommended Standards
- N-Nitroso Piperacillin impurity 103 (CAS CATO-C4X-1732103)
- Pyridoxine Impurity 6 (CAS 23429-05-2)
- Oxiracetam Impurity 9 (CAS 142274-07-5)
- 2-Oxohistidine (CAS 181996-08-7)
- Vericiguat Impurity 18 (CAS CATO-C4X-289618)
- Sildenafil Impurity C31 (CAS 2196244-90-1)
- Atogepant Impurity 32 (CAS 1375471-02-5)
- methyl 1-ethyl-4-iodo-1h-pyraZole-5-carboxylate (CAS 1354704-69-0)
- 1-(7-Hydroxy-2-(methoxymethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)ethan-1-one (CAS 1211450-09-7)
- trans-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene-d (CAS 861441-06-7)
- 4-Cyclopropoxy-6-ethylpicolinamide (CAS 1243289-33-9)
- 1-Methyl-4-oxo-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-7-carboxylic acid (CAS 925917-49-3)
- Tert-butyl 9-oxo-2,8-diazaspiro[4.6]Undecane-2-carboxylate (CAS 1341039-06-2)
- Semaglutide impurity 37 (CAS CATO-C4X-222637)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com