Fluralaner Impurity 8 CAS CATO-C4X-21808
| CAS No. | CATO-C4X-21808 |
| Molecular Formula | C18H10Cl2F6N2O2 |
| Molecular Weight | 471.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Fluralaner Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Fluralaner Impurity 8 (CAS CATO-C4X-21808, C18H10Cl2F6N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Fluralaner Impurity 8 (C18H10Cl2F6N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H10Cl2F6N2O2 |
| Molecular Weight | 471.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Fluralaner Standards
- Fluralaner impurity 39 (CAS CATO-C4X-218039)
- Fluralaner Impurity 10 (CAS 864731-37-3)
- Fluralaner impurity 31 (CAS CATO-C4X-218031)
- Fluralaner impurity 43 (CAS CATO-C4X-218043)
- Fluralaner impurity 41 (CAS CATO-C4X-218041)
- Fluralaner Impurity 50 (CAS 1309959-46-3)
- Fluralaner Impurity N3 (CAS 864725-61-1)
- Fluralaner Impurity 53 (CAS CATO-C4X-218053)
Recommended Standards
- N-(2-(2,2-dichloroacetamido)ethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 338404-73-2)
- Avanafil Impurity 116 (CAS CATO-C4X-1118116)
- 3-Chloro-1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-6-(trifluoromethyl)-1,2-dihydroquinoxalin-2-one (CAS 337921-03-6)
- tert-Butyl 4,6-bis(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dihydroisoindole-2-carboxylate (CAS 2377610-90-5)
- Eribulin Impurity 2 (CAS 1534341-96-2)
- Relebactam Impurity 74 (CAS CATO-C4X-214474)
- Ruxolitinib Impurity 88 (CAS CATO-C4X-205888)
- 2-(3-Nitrophenyl)propanoyl chloride (CAS 156516-83-5)
- 5,6,7,8-Tetrahydroimidazo[1,2-a]pyridin-7-ol (CAS 1785629-71-1)
- 3-isopropoxypropan-1-amine hydrochloride (CAS 226931-60-8)
- Balsalazide Impurity 7 (CAS CATO-C4X-15547)
- 7-Amino-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide (CAS 1050910-66-1)
- 8-O-Methyl-urolithin C (CAS 713519-19-8)
- Peptide 434 (CAS CATO-CPTD788434)
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