4-(4-Methylphenoxy)-2-(trifluoromethyl)quinazoline CAS 337925-03-8

Description

Compared with other compounds in its class, the molecular weight of 304.27 g/mol gives 4-(4-Methylphenoxy)-2-(trifluoromethyl)quinazoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-(4-Methylphenoxy)-2-(trifluoromethyl)quinazoline (CAS 337925-03-8), molecular formula C16H11F3N2O and molecular weight 304.27 g/mol, is a CATO reference standard with documented purity and traceability.

4-(4-Methylphenoxy)-2-(trifluoromethyl)quinazoline (C16H11F3N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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