(Z)-1-[(4-Cyano-5-methyl-1,2-thiazol-3-yl)sulfonyl]-N-[4-(trifluoromethoxy)phenyl]methanecarbohydrazonoyl cyanide CAS 337928-31-1
| CAS No. | 337928-31-1 |
| Molecular Formula | C14H8F3N5O3S2 |
| Molecular Weight | 415.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(Z)-1-[(4-Cyano-5-methyl-1,2-thiazol-3-yl)sulfonyl]-N-[4-(trifluoromethoxy)phenyl]methanecarbohydrazonoyl cyanide (CAS 337928-31-1), molecular formula C14H8F3N5O3S2 and molecular weight 415.37 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, (Z)-1-[(4-Cyano-5-methyl-1,2-thiazol-3-yl)sulfonyl]-N-[4-(trifluoromethoxy)phenyl]methanecarbohydrazonoyl cyanide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 415.37 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), (Z)-1-[(4-Cyano-5-methyl-1,2-thiazol-3-yl)sulfonyl]-N-[4-(trifluoromethoxy)phenyl]methanecarbohydrazonoyl cyanide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H8F3N5O3S2 |
| Molecular Weight | 415.37 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Z Standards
- N-(1-Cyano-1-cyclopropylethyl)-2-((2-methyl-5-(thiophen-2-yl)thieno[2,3-d]pyrimidin-4-yl)thio)acetamide (CAS 851281-47-5)
- 4-Cyano-N-(1-(1-(p-tolyl)-1H-1,2,3-triazole-4-carbonyl)piperidin-4-yl)benzamide (CAS 1251624-64-2)
- Methyl 2-({3-cyano-4-[3-(trifluoromethyl)phenyl]pyridin-2-yl}sulfanyl)benzoate (CAS 478245-75-9)
- N-(3-cyano-4-((3-(trifluoromethyl)phenyl)thio)phenyl)-4-fluorobenzamide (CAS 320421-64-5)
- 1-(4-Cyano-3-(trifluoromethyl)phenyl)-3-(3-cyano-4-(trifluoromethyl)phenyl)thiourea (CAS 1415564-70-3)
- 1-[(2'-Cyano-1,1'-biphenyl-4-yl)methyl]-2-ethoxy-d5-7-benzimidazolecarboxylic Acid Methyl Ester (CAS 1794783-33-7)
- 2-((4'-Cyano-[1,1'-biphenyl]-4-yl)oxy)-N-(2-((2,3-dimethylphenyl)amino)-2-oxoethyl)acetamide (CAS 851184-73-1)
- Ethyl 5-cyano-2-phenyl-6-[4-(pyridin-2-yl)piperazin-1-yl]pyridine-3-carboxylate (CAS 477866-20-9)
Recommended Standards
- (2E)-N-[3,5-Bis(trifluoromethyl)phenyl]-3-[4-(2-methylpropyl)phenyl]prop-2-enamide (CAS 329059-01-0)
- [5-[(E)-2-cyanovinyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-naphthyl] 2,2-dimethylpropanoate (CAS 2763158-48-9)
- Eleclazine (CAS 1443211-72-0)
- Pantoprazole Impurity 6 (CAS 953787-55-8)
- 2-((5-Bromo-2-hydroxybenzylidene)amino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile (CAS 294651-50-6)
- 5-(Piperidin-1-yl)picolinic acid (CAS 1273016-15-1)
- 1',4-Dimethylspiro[indoline-3,4'-piperidine] (CAS 1186499-24-0)
- Azd3463 (CAS 1356962-20-3)
- Methyl 2-(2-((3,5-dimethylisoxazol-4-yl)(hydroxy)methyl)benzofuran-5-yl)acetate (CAS 1421949-05-4)
- N-Boc-L-Homoserine Methyl Ester (CAS 120042-11-7)
- 4-methyl-1-(pyrrolidin-2-ylmethyl)-1H-pyrazole (CAS 1247146-12-8)
- 2-Cyanobenzohydrazide (CAS 19731-00-1)
- 3-(tert-Butyl)-4-cyclopropoxypyridin-2-amine (CAS 1243461-08-6)
- FMRF-Like Neuropeptide (CAS 121801-61-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com