4-(4-Methoxyphenyl)-6-(morpholin-4-yl)-2-(pyridin-2-yl)pyrimidine-5-carbonitrile CAS 338394-87-9
| CAS No. | 338394-87-9 |
| Molecular Formula | C21H19N5O2 |
| Molecular Weight | 373.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(4-Methoxyphenyl)-6-(morpholin-4-yl)-2-(pyridin-2-yl)pyrimidine-5-carbonitrile (CAS 338394-87-9) is a high-purity analytical reference standard with the molecular formula C21H19N5O2 and a molecular weight of 373.41 g/mol.
The molecular framework of 4-(4-Methoxyphenyl)-6-(morpholin-4-yl)-2-(pyridin-2-yl)pyrimidine-5-carbonitrile (C21H19N5O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H19N5O2 |
| Molecular Weight | 373.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 5 |
Related Methoxyphenyl Standards
- 3-(3-Methoxyphenyl)-N-(naphthalen-1-yl)-2-(2H-1,2,3,4-tetrazol-5-yl)propanamide (CAS 483993-58-4)
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Recommended Standards
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- 2-{[4-(4-benzylpiperazino)-3-nitrophenyl]methylene}malononitrile (CAS 329778-08-7)
- tert-Butyl (1-(2-amino-1-(4-(trifluoromethyl)phenyl)ethyl)pyrrolidin-3-yl)carbamate (CAS 886365-38-4)
- 4-amino-5-cyano-2-sulfanyl-3-azaspiro[5.5]undeca-1,4-diene-1-carboxamide (CAS 885460-90-2)
- 3-(9-Ethyl-9H-carbazol-3-yl)-2-mercapto-3H-quinazolin-4-one (CAS 438030-15-0)
- Pexacerfont (CAS 459856-18-9)
- (E)-4-{4-[(3-Methylbutanoyl)amino]anilino}-4-oxo-2-butenoic acid 3789AF 940213-50-3 C15H18N2O4 (CAS 940213-50-3)
- N,2-Dimethyl-1H-benzo[d]imidazol-1-amine (CAS 213206-23-6)
- 3-(4-Bromophenyl)piperidine (CAS 769944-72-1)
- 5-(3-Chloro-2-methylphenyl)furan-2-carboxylic acid (CAS 353761-03-2)
- 3-CHLORO-5-NITROPICOLINALDEHYDE (CAS 141238-22-4)
- N,N-Dimethyl-4-(1-methyl-1H-indol-2-yl)aniline (CAS 61843-44-5)
- Acetyl Tetrapeptide-11 (CAS 928006-88-6)
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