1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrole-2-carboxylic acid CAS 338397-41-4
| CAS No. | 338397-41-4 |
| Molecular Formula | C11H6ClF3N2O2 |
| Molecular Weight | 290.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrole-2-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrole-2-carboxylic acid (CAS 338397-41-4), a certified reference material (molecular formula C11H6ClF3N2O2, MW 290.63 g/mol) for analytical method development and quality control.
Structurally, 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrole-2-carboxylic acid (C11H6ClF3N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 290.63 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrole-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H6ClF3N2O2 |
| Molecular Weight | 290.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 5-Chloro-1-phenyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 1152972-16-1)
- 5-Chloro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxylic acid (CAS 1355224-27-9)
- 4-Chloro-6-methyl-5-nitro-2-(trifluoromethyl)quinoline (CAS 175203-61-9)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazole-4-carboxamide (CAS 400078-97-9)
- 1-{3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1,2-oxazol-5-yl}ethan-1-one (CAS 477872-99-4)
- 5-[4-Chloro-2-(trifluoromethyl)phenyl]-2-furancarboxylic Acid (CAS 1094391-72-6)
- 3-Chloro-N-(4-fluorophenyl)-5-(trifluoromethyl)-2-pyridinamine (CAS 1219976-66-5)
- 2'-Chloro-4'-(difluoromethoxy)-2,3-difluoro-1,1'-biphenyl (CAS 1261573-51-6)
Recommended Standards
- 1-(4-Chlorophenyl)-5-(trifluoromethyl)-1h-pyrazole-4-carboxylic acid (CAS 98534-80-6)
- 1-(3-Chlorophenyl)-5-(trifluoromethyl)-1h-pyrazole-4-carboxylic acid (CAS 98534-82-8)
- 3-(2-Chlorophenyl)-6-(trifluoromethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 860609-30-9)
- 3-(3-Chlorophenyl)-6-(trifluoromethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 860609-34-3)
- 3-(Pyrazin-2-yloxy)benzoic acid (CAS 1250986-82-3)
- 1,3-Dihydrobenzo[c]isothiazole 2,2-dioxide (CAS 111248-89-6)
- 4-Chloro-6-(methylamino)pyrimidine-5-carbonitrile (CAS 872890-15-8)
- Naphthalen-1-yl(naphthalen-2-yl)methanone (CAS 605-79-8)
- Benzyl (2-(2-amino-N-isopropylacetamido)cyclohexyl)carbamate (CAS 1353964-06-3)
- 4-(Benzyloxy)phenyl cyclohexanecarboxylate (CAS 354796-53-5)
- N-(5-bromo-2-methoxybenzyl)-1-methoxypropan-2-amine hydrobromide (CAS 1609403-35-1)
- 506-87-6 PDP691CN28 Ammonium carbonate Diammonium carbonate Carbonic acid, diammonium salt Carbonic acid, ammonium salt (1:2) AI3-25347 Ammonia sesquicarbonate Ammoniumcarbonat [German] Carbonate d'ammoniaque [French] Caswell No. 042 CCRIS 7328 EINECS 208-058-0 EPA Pesticide Chemical Code 073501 HSDB 6305 Ammoniumcarbonat Carbonate d'ammoniaque UNII-PDP691CN28 Crystal ammonia Ammonium carbonicum EC 208-058-0 (CAS 506-87-6)
- N-Methylpyrazolo[1,5-a]pyridine-2-carboxamide (CAS 1204943-50-9)
- Liraglutide Sodium Salt (CAS 204656-20-2（free base）)
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