1-{3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1,2-oxazol-5-yl}ethan-1-one CAS 477872-99-4
| CAS No. | 477872-99-4 |
| Molecular Formula | C11H6ClF3N2O2 |
| Molecular Weight | 290.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-{3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1,2-oxazol-5-yl}ethan-1-one (CAS 477872-99-4) is a high-purity analytical reference standard with the molecular formula C11H6ClF3N2O2 and a molecular weight of 290.63 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 1-{3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1,2-oxazol-5-yl}ethan-1-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 290.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-{3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1,2-oxazol-5-yl}ethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H6ClF3N2O2 |
| Molecular Weight | 290.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related chloro Standards
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- 5-[4-Chloro-2-(trifluoromethyl)phenyl]-2-furancarboxylic Acid (CAS 1094391-72-6)
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Recommended Standards
- 3-(2-Chlorophenyl)-6-(trifluoromethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 860609-30-9)
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- 3-(3-Chlorophenyl)-6-(trifluoromethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 860609-34-3)
- 1-(3-Chlorophenyl)-5-(trifluoromethyl)-1h-pyrazole-4-carboxylic acid (CAS 98534-82-8)
- (Z)-{2,2-bis[(2,4-dimethylphenyl)carbamoyl]ethylidene}(methyl)oxidoazanium (CAS 400088-03-1)
- 5-(4-Methoxybenzyl)-2-pyrrolidin-2-yl-1,3-oxazole dihydrochloride (CAS 1982761-14-7)
- 1,10-Decyldiphosphonic acid (CAS 5943-21-5)
- 1-(3-Bromo-4-(bromomethyl)phenyl)ethan-1-one (CAS 909190-70-1)
- (R)-3-Amino-5-methyl-2,3-dihydrobenzo[b][1,4]oxazepin-4(5H)-one (CAS 796038-22-7)
- Ethyl 2-(3,5-difluorophenyl)acetate (CAS 139368-37-9)
- 2,4,6-Trioctyl-1,3,5,2,4,6-trioxatriborinane (CAS 142169-80-0)
- 898755-91-4 1-[3,5-Bis(trifluoromethyl)phenyl]-4-(5,5-dimethyl-1,3-dioxan-2-yl)butan-1-one DTXSID00646008 (CAS 898755-91-4)
- N-[(benzylamino)carbonyl]acrylamide (CAS 1000931-67-8)
- Peptide 438 (CAS CATO-CPTD788438)
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