N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N'-methyl-3-(3-methyl-5-oxo-1-phenyl-1,2,4-triazolidin-3-yl)-4,5-dihydroisoxazole-5-carbohydrazide CAS 338400-95-6
| CAS No. | 338400-95-6 |
| Molecular Formula | C20H19ClF3N7O3 |
| Molecular Weight | 497.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N'-methyl-3-(3-methyl-5-oxo-1-phenyl-1,2,4-triazolidin-3-yl)-4,5-dihydroisoxazole-5-carbohydrazide (CAS 338400-95-6), a certified reference material (molecular formula C20H19ClF3N7O3, MW 497.86 g/mol) for analytical method development and quality control.
The molecular framework of N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N'-methyl-3-(3-methyl-5-oxo-1-phenyl-1,2,4-triazolidin-3-yl)-4,5-dihydroisoxazole-5-carbohydrazide (C20H19ClF3N7O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H19ClF3N7O3 |
| Molecular Weight | 497.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 7 |
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Recommended Standards
- tert-Butyl 4-(4-chlorophenyl)-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine-1-carboxylate (CAS 917899-36-6)
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- (2S,3R,4S,5R,6R)-2-(((2R,3S,4R,5R,6S)-6-(2-chloro-4-nitrophenoxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 120583-41-7)
- 4-(Difluoromethyl)-3-iodo-5-methylpicolinamide (CAS 1805102-71-9)
- 2-((4-Fluorophenyl)sulfonyl)-1,2,3,4-tetrahydroisoquinoline (CAS 313981-60-1)
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- 7-METHOXY-2,3,4,5-TETRAHYDRO-1H-BENZO[C]AZEPINE HCL (CAS 57644-67-4)
- Hydroxychloroquine Impurity 43 (CAS CATO-C4X-183543)
- (4-(4-(2-Hydroxyethyl)piperazine-1-carbonyl)phenyl)boronic acid hydrochloride (CAS 913835-44-6)
- O-(3-Cyano-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridin-2-yl) O,O-diethyl phosphorothioate (CAS 286435-85-6)
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- 1-(4-(Methylthio)phenyl)ethanone (CAS 1778-09-2)
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