4-Chloro-2-(difluoro(4-fluorophenyl)methyl)-7-methylquinazoline CAS 1241915-17-2
| CAS No. | 1241915-17-2 |
| Molecular Formula | C16H10ClF3N2 |
| Molecular Weight | 322.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 322.71 g/mol gives 4-Chloro-2-(difluoro(4-fluorophenyl)methyl)-7-methylquinazoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Chloro-2-(difluoro(4-fluorophenyl)methyl)-7-methylquinazoline (CAS 1241915-17-2), molecular formula C16H10ClF3N2 and molecular weight 322.71 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Chloro-2-(difluoro(4-fluorophenyl)methyl)-7-methylquinazoline (C16H10ClF3N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Chloro-2-(difluoro(4-fluorophenyl)methyl)-7-methylquinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H10ClF3N2 |
| Molecular Weight | 322.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- Ethyl (2S,5S)-5-(5-chloro-2-(trifluoromethyl)pyridin-4-yl)pyrrolidine-2-carboxylate (CAS 1648890-21-4)
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- (2Z)-2-(4-Chlorophenyl)-3-{[3-(trifluoromethyl)phenyl]amino}prop-2-enenitrile (CAS 338403-10-4)
- 3-(2-Chlorophenyl)-2-methyl-5-(trifluoromethyl)quinoxaline (CAS 1065482-55-4)
- 1-[4-(trifluoromethyl)-1,3-thiazol-2-yl]piperazine (CAS 107507-53-9)
- 3-fluoro-4-(pyridin-3-ylmethoxy)aniline,HCl (CAS 1431967-87-1)
- 1-(4-(2-Aminopropan-2-yl)piperidin-1-yl)ethan-1-one (CAS 1499215-05-2)
- H-Gly-Pro-OH (CAS 704-15-4)
- 2-(3-Nitrophenyl)-1h-imidazole hydrochloride (CAS 1193389-94-4)
- 2-Cyano-N-(2-phenoxyphenyl)acetamide (CAS 380342-42-7)
- (S)-N-(1-(4-Methylquinazolin-2-yl)-2-phenylethyl)formamide (CAS 923603-71-8)
- (3R,4S)-4-Methoxytetrahydrofuran-3-amine (CAS 1909294-55-8)
- 2-Amino-2-(4-methylcyclohexyl)acetamide (CAS 1479474-62-8)
- Liraglutide Impurity 13 TFA Salt (CAS CATO-C4X-199213)
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