5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-[(1E)-(methoxyamino)methylidene]-4,5-dihydro-1,2-oxazole-3-carboxamide CAS 338410-28-9
| CAS No. | 338410-28-9 |
| Molecular Formula | C13H13ClF3N5O3 |
| Molecular Weight | 379.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-[(1E)-(methoxyamino)methylidene]-4,5-dihydro-1,2-oxazole-3-carboxamide (CAS 338410-28-9), molecular formula C13H13ClF3N5O3 and molecular weight 379.72 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-N-[(1E)-(methoxyamino)methylidene]-4,5-dihydro-1,2-oxazole-3-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 379.72 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H13ClF3N5O3 |
| Molecular Weight | 379.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
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Recommended Standards
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- 2-((2-Chlorobenzyl)sulfonyl)-1-nitro-4-(trifluoromethyl)benzene (CAS 866132-61-8)
- 2-[4-(1-aminoethyl)phenoxy]acetamide (CAS 954569-98-3)
- 2-Deoxy-5-[3-[[[(3,6-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9-[9H]xanthen]-5-yl)amino]thioxomethyl]amino]-1-propynyl]uridine 5-(Tetrahydrogen Triphosphate) (CAS 137993-59-0)
- 6-((tert-Butoxycarbonyl)amino)-4-chloropicolinic acid (CAS 1060801-16-2)
- Succinic Acid Monobenzyl Ester (CAS 103-40-2)
- 4-(2,6-Difluorobenzamido)-1H-pyrazole-3-carboxylic acid (CAS 825618-95-9)
- n1,n1,4,4-Tetramethylpentane-1,5-diamine (CAS 1495166-12-5)
- Methyl 5-(3,4-dichlorophenyl)-1-(p-tolyl)-1H-pyrazole-3-carboxylate (CAS 318256-24-5)
- (2-Methoxyphenyl)(4-(thiomorpholinomethyl)phenyl)methanone (CAS 898782-31-5)
- 1-(2-Morpholinoethyl)-1H-imidazole-4-carboxylic acid (CAS 1422023-27-5)
- Semaglutide impurity 204 (CAS CATO-C4X-2226204)
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