(3E)-3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methylidene}-1,2,3,4-tetrahydroquinoxalin-2-one CAS 338410-37-0
| CAS No. | 338410-37-0 |
| Molecular Formula | C15H9ClF3N3O |
| Molecular Weight | 339.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (3E)-3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methylidene}-1,2,3,4-tetrahydroquinoxalin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(3E)-3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methylidene}-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 338410-37-0), molecular formula C15H9ClF3N3O and molecular weight 339.70 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (3E)-3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methylidene}-1,2,3,4-tetrahydroquinoxalin-2-one (C15H9ClF3N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 339.70 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H9ClF3N3O |
| Molecular Weight | 339.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related E Standards
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Recommended Standards
- 3-Bromo-6-chloro-2-fluorophenoxy(tert-butyl)dimethylsilane (CAS 1881320-40-6)
- Vilanterol Impurity 68 (CAS CATO-C4X-193568)
- Diethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)malonate (CAS 172527-71-8)
- tert-Butyl (4-chloro-3-(difluoromethoxy)-5-nitropyridin-2-yl)carbamate (CAS 1956322-97-6)
- 5-(5-Methylisoxazole-3-carboxamido)pentanoic acid (CAS 1343038-98-1)
- 6-(trifluoromethoxy)benzofuran-3-one (CAS 857062-56-7)
- 2-[4-(Benzyloxy)phenyl]cyclopropan-1-amine (CAS 1157140-21-0)
- 3-bromo-4-methyl-1H-pyrazole (CAS 5932-20-7)
- 2-amino-N-ethyl-3,3,3-trifluoro-2-methylpropanamide (CAS 1520596-03-5)
- 4-Methylenechroman (CAS 87280-12-4)
- tert-Butyl (5-amino-2,3-dimethylphenyl)carbamate (CAS 1936384-11-0)
- 4-Chloro-3-(4-formylphenyl)benzoic acid (CAS 1261921-72-5)
- Formoterol impurity 112 (CAS 63192-58-5)
- (Tyr?)-C-Peptide (dog) (CAS 101135-67-5)
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