3-Bromo-6-chloro-2-fluorophenoxy(tert-butyl)dimethylsilane CAS 1881320-40-6
| CAS No. | 1881320-40-6 |
| Molecular Formula | C12H17BrClFOSi |
| Molecular Weight | 339.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Bromo-6-chloro-2-fluorophenoxy(tert-butyl)dimethylsilane (CAS 1881320-40-6) is a high-purity analytical reference standard with the molecular formula C12H17BrClFOSi and a molecular weight of 339.70 g/mol.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, 3-Bromo-6-chloro-2-fluorophenoxy(tert-butyl)dimethylsilane is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 339.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H17BrClFOSi |
| Molecular Weight | 339.70 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl/Br-containing |
Related Bromo Standards
- 8-Bromo-3-butyl-1-chloro-5,10-dihydroimidazo[1,5-b]isoquinoline (CAS 1246820-05-2)
- 3-Bromo-4-chloro-5-(piperidin-1-ylsulfonyl)pyridine (CAS 1352530-97-2)
- 1-(4-Bromo-2-chlorobenzenesulfonyl)piperazine (CAS 731003-83-1)
- 1-[(4-Bromo-3-chlorophenyl)sulfonyl]piperazine (CAS 942473-64-5)
- 3-Bromo-5-((4-chlorophenyl)sulfonyl)-1,2,4-thiadiazole (CAS 1000574-66-2)
- 5-Bromo-2-[(2-methylbenzyl)oxy]benzoyl chloride (CAS 1160250-54-3)
- 5-Bromo-2-[(3-methylbenzyl)oxy]benzoyl chloride (CAS 1160250-99-6)
- 6-Bromo-8-(chloromethyl)-2-phenyl-4h-benzo[d][1,3]dioxine (CAS 730950-04-6)
Recommended Standards
- 3-{2-[4-chloro-3-(trifluoromethyl)phenoxy]phenyl}-3-oxopropanenitrile (CAS 136562-66-8)
- (3E)-3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methylidene}-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 338410-37-0)
- Vilanterol Impurity 68 (CAS CATO-C4X-193568)
- 3-[(5-Chloro-2-hydroxyphenyl)methylidene]-6-(trifluoromethyl)-2,3-dihydro-1H-indol-2-one (CAS 860651-10-1)
- 4H-Pyrrolo[1,2-b]pyrazole-3-carboxylic acid, 5,6-dihydro-2-(2-pyridinyl)-, ethyl ester (CAS 700871-82-5)
- 7-Iodoisoindolin-1-one (CAS 866766-96-3)
- 2-[1-(2,3-Dimethoxybenzyl)-3-oxo-2-piperazinyl]-acetic acid (CAS 1042697-82-4)
- 4-Chloro-N-(4-hydroxynaphthalen-1-yl)-3-nitrobenzenesulfonamide (CAS 420092-79-1)
- 7-Isopropoxy-2H-chromen-2-one (CAS 87980-63-0)
- (7-Fluoro-6-methoxyquinolin-8-yl)boronic acid (CAS 2773311-28-5)
- [5-Furan-2-yl-4-(2-methoxy-ethyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-acetic acid (CAS 462068-08-2)
- Paliperidone Impurity 109 HCl (CAS CATO-C4X-1724109)
- N,N,N'-trimethylhydrazinecarboximidamide (CAS 744989-34-2)
- Semaglutide impurity 87 (CAS CATO-C4X-222687)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com