4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](cyano)methyl}phenyl acetate CAS 338410-39-2
| CAS No. | 338410-39-2 |
| Molecular Formula | C16H10ClF3N2O2 |
| Molecular Weight | 354.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](cyano)methyl}phenyl acetate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 354.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](cyano)methyl}phenyl acetate (CAS 338410-39-2), molecular formula C16H10ClF3N2O2 and molecular weight 354.71 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](cyano)methyl}phenyl acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H10ClF3N2O2 |
| Molecular Weight | 354.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related chloro Standards
- (3Z)-3-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methylhydrazin-1-ylidene}-2,3-dihydro-1H-indol-2-one (CAS 1048915-16-7)
- 2-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indol-3-yl)acetic acid (CAS 339099-14-8)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-methyl-4-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860789-81-7)
- 3-(4-Chloro-2-fluoro-5-mercaptophenyl)-1-methyl-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione (CAS 353292-92-9)
- 3-{1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-pyrrol-2-yl}-2-[(methoxyimino)methyl]acrylonitrile (CAS 339278-24-9)
- 4-Chloro-6-methyl-2-[3-(trifluoromethyl)benzyl]-2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-1,3-dione (CAS 261363-79-5)
- 353258-51-2 8-chloro-N-(2-pyridinylmethyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxamide KS-000030FV (CAS 353258-51-2)
- 3-((3-Chloro-4-fluorophenyl)sulfonyl)-7-hydroxy-2H-chromen-2-one (CAS 866346-86-3)
Recommended Standards
- 5-((4-Chlorophenoxy)methyl)-3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole (CAS 860784-34-5)
- 3-(2-Chlorophenyl)-7-hydroxy-8-methyl-2-(trifluoromethyl)-4h-chromen-4-one (CAS 328019-92-7)
- 5-(4-Chlorophenyl)-2-((1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)oxy)pyrimidine (CAS 477711-83-4)
- N1-[2-(4-cyanophenoxy)-5-(trifluoromethyl)phenyl]-2-chloroacetamide (CAS 218157-69-8)
- 2-(M-tolylthio)cyclopentan-1-one (CAS 1249812-38-1)
- (S)-2-methyl-4-((3-(4-(trifluoromethyl)phenyl)-9H-carbazol-9-yl)methyl)-4,5-dihydrooxazole (CAS 2357080-12-5)
- 2-(Difluoromethyl)pyrido[3,4-d]pyrimidin-4(3H)-one (CAS 1437482-82-0)
- 2-Chloro-6-fluorobenzene-1-thiol (CAS 1208075-39-1)
- Ethyl 2-(2-((4-fluorophenyl)amino)thiazol-4-yl)acetate (CAS 886499-02-1)
- 3-(4-Methyl-2-oxoquinolin-1(2H)-yl)propanoic acid (CAS 75371-21-0)
- 3-(aminomethyl)-1-methylpyrrolidin-3-ol (CAS 1342062-26-3)
- Tert-butyl 4-(((3-nitropyridin-2-yl)amino)methyl)piperidine-1-carboxylate (CAS 939986-18-2)
- 2-CHLORO-N-(3,5-DIMETHYLPHENYL)ACETAMIDE (CAS 174700-38-0)
- His-Aib-Semaglutide (CAS CATO-C4X-2226220)
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