3-(4-Chloro-2-fluoro-5-mercaptophenyl)-1-methyl-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione CAS 353292-92-9
| CAS No. | 353292-92-9 |
| Molecular Formula | C12H7ClF4N2O2S |
| Molecular Weight | 354.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-(4-Chloro-2-fluoro-5-mercaptophenyl)-1-methyl-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-(4-Chloro-2-fluoro-5-mercaptophenyl)-1-methyl-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione (CAS 353292-92-9) is a high-purity analytical reference standard with the molecular formula C12H7ClF4N2O2S and a molecular weight of 354.71 g/mol.
The molecular framework of 3-(4-Chloro-2-fluoro-5-mercaptophenyl)-1-methyl-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione (C12H7ClF4N2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H7ClF4N2O2S |
| Molecular Weight | 354.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- (3Z)-3-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methylhydrazin-1-ylidene}-2,3-dihydro-1H-indol-2-one (CAS 1048915-16-7)
- 2-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indol-3-yl)acetic acid (CAS 339099-14-8)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-methyl-4-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860789-81-7)
- 3-{1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1H-pyrrol-2-yl}-2-[(methoxyimino)methyl]acrylonitrile (CAS 339278-24-9)
- 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](cyano)methyl}phenyl acetate (CAS 338410-39-2)
- 4-Chloro-6-methyl-2-[3-(trifluoromethyl)benzyl]-2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-1,3-dione (CAS 261363-79-5)
- 353258-51-2 8-chloro-N-(2-pyridinylmethyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxamide KS-000030FV (CAS 353258-51-2)
- 3-((3-Chloro-4-fluorophenyl)sulfonyl)-7-hydroxy-2H-chromen-2-one (CAS 866346-86-3)
Recommended Standards
- 3-(2-Chlorophenyl)-7-hydroxy-8-methyl-2-(trifluoromethyl)-4h-chromen-4-one (CAS 328019-92-7)
- 5-((4-Chlorophenoxy)methyl)-3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole (CAS 860784-34-5)
- Acetic (tris(trimethylsilyl) orthosilicic) anhydride (CAS 74098-43-4)
- 5-(4-Chlorophenyl)-2-((1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)oxy)pyrimidine (CAS 477711-83-4)
- 3-chloro-3-[3-(difluoromethoxy)phenyl]prop-2-enenitrile (CAS 1158127-34-4)
- 2-(4-Methoxyphenyl)-5-methyl-1H-benzo[d]imidazole (CAS 53314-16-2)
- N-(Butan-2-yl)-3-methylaniline (CAS 205262-24-4)
- Methyl 3-amino-6-(5-methyl-2-furyl)-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylate (CAS 1428139-54-1)
- 5-Methyl-1-propyl-1H-pyrazol-3-ylamine 5-methyl-1-propyl-1 h-pyrazol-3-ylamine 5-methyl-1-propyl-1h-pyrazol-3-amine 943107-35-5 (CAS 943107-35-5)
- N-(2-Aminoethyl)-N-methyl-ethanolamine (CAS 5753-50-4)
- 2-Chloro-3-((2-hydroxypropyl)amino)naphthalene-1,4-dione (CAS 875440-38-3)
- 4-(4-Chlorophenyl)-2-[(E)-2-(dimethylamino)ethenyl]-6-methylpyridine-3,5-dicarbonitrile (CAS 337924-09-1)
- 1-(cyclopropylmethyl)imidazolidin-2-one (CAS 1547046-72-9)
- Semaglutide impurity 331 (CAS CATO-C4X-2226231)
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