2-(2-Chloropyridin-3-yl)-1-(4-methylbenzyl)-1H-benzo[d]imidazole CAS 338411-40-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-Chloropyridin-3-yl)-1-(4-methylbenzyl)-1H-benzo[d]imidazole.

2-(2-Chloropyridin-3-yl)-1-(4-methylbenzyl)-1H-benzo[d]imidazole (CAS 338411-40-8) is a high-purity analytical reference standard with the molecular formula C20H16ClN3 and a molecular weight of 333.81 g/mol.

2-(2-Chloropyridin-3-yl)-1-(4-methylbenzyl)-1H-benzo[d]imidazole (C20H16ClN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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