1-(3-Chlorophenyl)-5-(3-(trifluoromethyl)phenyl)-1H-tetrazole CAS 338411-41-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(3-Chlorophenyl)-5-(3-(trifluoromethyl)phenyl)-1H-tetrazole.

1-(3-Chlorophenyl)-5-(3-(trifluoromethyl)phenyl)-1H-tetrazole (CAS 338411-41-9), molecular formula C14H8ClF3N4 and molecular weight 324.69 g/mol, is a CATO reference standard with documented purity and traceability.

1-(3-Chlorophenyl)-5-(3-(trifluoromethyl)phenyl)-1H-tetrazole (C14H8ClF3N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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