7-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-4-methyl-2-(methylthio)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine CAS 338416-24-3
| CAS No. | 338416-24-3 |
| Molecular Formula | C20H16ClF3N4OS |
| Molecular Weight | 452.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 452.88 g/mol gives 7-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-4-methyl-2-(methylthio)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 7-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-4-methyl-2-(methylthio)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine (CAS 338416-24-3), a certified reference material (molecular formula C20H16ClF3N4OS, MW 452.88 g/mol) for analytical method development and quality control.
The molecular framework of 7-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-4-methyl-2-(methylthio)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine (C20H16ClF3N4OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-4-methyl-2-(methylthio)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H16ClF3N4OS |
| Molecular Weight | 452.88 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N'-methyl-2-(p-tolylthio)nicotinohydrazide (CAS 1024403-13-1)
- N-(4-chloro-3-(trifluoromethyl)phenyl)-2-((7-cyano-3,4-dihydro-2H-1,4-ethano-1,5-naphthyridin-6-yl)thio)acetamide (CAS 728888-23-1)
- 3-(3-Chloro-2-(cyclopropylamino)pyridin-4-yl)-2-(4-methoxybenzyl)-5-methyl-1,2-dihydro-4H-pyrazolo[3,4-d]pyrimidine-4,6(5H)-dione (CAS 2316847-93-3)
- 5-Chloro-4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 2771080-69-2)
- 3-(3-Chloro-2-methylphenyl)-N'-[(1E)-(3,4-difluorophenyl)methylidene]-4-oxo-3,4-dihydrophthalazine-1-carbohydrazide (CAS 672925-68-7)
- Methyl 7-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-5,8-dioxo-hexahydro-1H-[1,3]thiazolo[3,4-a]pyrazine-3-carboxylate (CAS 318247-37-9)
- Methyl 4-chloro-1-trityl-1H-pyrrolo[2,3-b]pyridine-5-carboxylate (CAS 2436537-65-2)
- 4-Chloro-N-[(5-{[(4-fluorophenyl)methyl]sulfanyl}-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl)methyl]benzene-1-sulfonamide (CAS 338422-28-9)
Recommended Standards
- Dapagliflozin Impurity 117 (CAS 2377899-45-9)
- 5-(4-Chlorophenyl)-4-(3-fluoro-4-methoxybenzoyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 609793-43-3)
- Ertugliflozin impurity 22 (CAS 1298086-28-8)
- Ertugliflozin Impurity 50 (CAS 1298086-33-5)
- 4-{[(Butan-2-yl)amino]methyl}-2-methoxyphenol hydrochloride (CAS 1240567-78-5)
- Benzo[4,5]thiazolo[2,3-c][1,2,4]triazol-3-amine (CAS 105873-32-3)
- tert-Butyl 5-bromo-3,4-dihydro-1H-pyrido[3,4-b]indole-2(9H)-carboxylate (CAS 2251731-93-6)
- Methyl 5-amino-2-morpholinobenzoate (CAS 83909-35-7)
- tert-Butyl ((6-phenylpyridin-3-yl)methyl)carbamate (CAS 1252572-73-8)
- 5-Fluoro-2-(methoxymethyl)pyrimidin-4-ol (CAS 1150618-10-2)
- 5-(((9H-Fluoren-9-yl)methoxy)carbonyl)-5-azaspiro[2.4]heptane-7-carboxylic acid (CAS 2138525-93-4)
- 6-Sulfatoxy Melatonin-d4 (CAS 1309935-98-5)
- N-(1H-1,2,3-triazol-5-ylmethyl)aniline (CAS 165397-77-3)
- Semaglutide impurity 98 (CAS CATO-C4X-222698)
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