6-Amino-4-((2,4-dichlorophenoxy)methyl)-2-oxo-1-phenyl-1,2-dihydropyrimidine-5-carbonitrile CAS 338418-69-2
| CAS No. | 338418-69-2 |
| Molecular Formula | C18H12Cl2N4O2 |
| Molecular Weight | 387.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Amino-4-((2,4-dichlorophenoxy)methyl)-2-oxo-1-phenyl-1,2-dihydropyrimidine-5-carbonitrile (CAS 338418-69-2) is a high-purity analytical reference standard with the molecular formula C18H12Cl2N4O2 and a molecular weight of 387.22 g/mol.
6-Amino-4-((2,4-dichlorophenoxy)methyl)-2-oxo-1-phenyl-1,2-dihydropyrimidine-5-carbonitrile (C18H12Cl2N4O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 6-Amino-4-((2,4-dichlorophenoxy)methyl)-2-oxo-1-phenyl-1,2-dihydropyrimidine-5-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H12Cl2N4O2 |
| Molecular Weight | 387.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
- 4-(1-(2,5-Dichlorophenyl)-6-hydroxy-1H-indazol-3-yl)benzene-1,3-diol (CAS 680610-83-7)
- N1-(4,6-Dichloro-2-phenylpyrimidin-5-yl)-N1-phenyloxalamide (CAS 59808-66-1)
- 10-(2-((4,6-Dichloro-1,3,5-triazin-2-yl)oxy)ethyl)acridin-9(10H)-one (CAS 915691-79-1)
- Tert-butyl 4-(5-bromo-3-nitropyridin-2-yl)piperazine-1-carboxylate (CAS 1221792-73-9)
- tert-Butyl 5-bromo-1H-benzo[d]imidazole-1-carboxylate (CAS 942590-05-8)
- Allyl 3-(hydroxymethyl)piperazine-1-carboxylate (CAS 885275-39-8)
- 6-Cyclohexyl-8-fluoro-2,3-dimethylquinolin-4-ol (CAS 648942-35-2)
- (r)-4-(1-Amino-2-hydroxyethyl)-2-nitrophenol (CAS 1212825-54-1)
- Memantine impurity 58 (CAS 49764-18-3)
- 4-Chloro-N-isopropyl-5-methoxypyrimidin-2-amine (CAS 1353945-30-8)
- 2-Methoxyphenyl 2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-5-carboxylate (CAS 1093406-46-2)
- (2-ethoxy-2-oxoacetyl)alanine (CAS 774596-23-5)
- 2-(3-(Benzyloxy)-4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1005010-03-6)
- Semaglutide Impurity 129 (CAS 2490269-79-7)
Why CATO?
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