5,6-Bis(3,4-dichlorophenyl)-2-(2-hydroxyethyl)-3-oxo-2,3-dihydropyridazine-4-carbonitrile CAS 75660-46-7
| CAS No. | 75660-46-7 |
| Molecular Formula | C19H11Cl4N3O2 |
| Molecular Weight | 455.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5,6-Bis(3,4-dichlorophenyl)-2-(2-hydroxyethyl)-3-oxo-2,3-dihydropyridazine-4-carbonitrile (CAS 75660-46-7), molecular formula C19H11Cl4N3O2 and molecular weight 455.12 g/mol, is a CATO reference standard with documented purity and traceability.
5,6-Bis(3,4-dichlorophenyl)-2-(2-hydroxyethyl)-3-oxo-2,3-dihydropyridazine-4-carbonitrile (C19H11Cl4N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H11Cl4N3O2 |
| Molecular Weight | 455.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Bis Standards
- (5Z)-5-{[(3,4-dichlorophenyl)amino]methylidene}-4-(4-fluorophenyl)-1-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrol-2-one (CAS 339012-09-8)
- 1-(3,4-Dichlorophenyl)-2-((5-(pyridin-4-yl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)ethanone (CAS 575469-40-8)
- 1-[(2,4-Dichlorophenyl)methyl]-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (CAS 338418-91-0)
- 1-[(2,6-Dichlorophenyl)methyl]-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (CAS 338419-07-1)
- 1-[(3,4-Dichlorophenyl)methyl]-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (CAS 338418-94-3)
- 1-Benzyl-3'-(3,4-dichlorophenyl)spiro[indoline-3,2'-thiazolidine]-2,4'-dione (CAS 861211-75-8)
- 3-(2-{[(2,4-dichlorophenyl)methyl]sulfanyl}pyrimidin-4-yl)-1-(4-methylphenyl)-1,4-dihydropyridazin-4-one (CAS 478077-67-7)
- 4-[5-(2,4-Dichlorophenyl)-1H-pyrazol-3-yl]-1-{[3-(trifluoromethyl)phenyl]methyl}piperidine (CAS 1025724-79-1)
Recommended Standards
- Olodaterol Impurity 17 (CAS CATO-C4X-194317)
- 4-((3,5-Dibromo-2-hydroxybenzylidene)amino)-3-(pyridin-2-yl)-1H-1,2,4-triazole-5(4H)-thione (CAS 613248-46-7)
- Olodaterol Impurity 16 (CAS CATO-C4X-194316)
- 3,10-Dibromo-6-phenyl-6H-benzo[5,6][1,3]oxazino[3,4-a]indole (CAS 1369594-56-8)
- 2-Bromo-N-(4-fluorophenyl)propanamide (CAS 905797-71-9)
- 1-(3,4-Methylenedioxyphenyl)butane (CAS 16929-05-8)
- 1-Methyl-3-(pentafluoroethyl)-4-(trifluoromethyl)-1h-pyrazol-5-amine (CAS 132631-86-8)
- Acetic acid ethenyl ester, polymer with chloroethene and ethene (CAS 25085-46-5)
- 4-Bromo-2-methoxypyridine (CAS 100367-39-3)
- n-(2-Methoxybenzyl)-3-methylbutan-1-amine (CAS 932215-89-9)
- 3-Benzyl-1,2,4-oxadiazole-5-carbaldehyde (CAS 103499-30-5)
- 1-(2,5-Dimethylbenzyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1338654-81-1)
- 1-Methyl-3-(3-methylbut-3-en-1-yl)benzene (CAS 113947-88-9)
- Semaglutide impurity 100 (CAS CATO-C4X-2226100)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com