4-Chloro-6-(4-methoxyphenyl)-2-phenylpyrimidine-5-carbonitrile CAS 320418-90-4

Purity 97%+In StockPharmaceutical Standards
CAS No.320418-90-4
Molecular FormulaC18H12ClN3O
Molecular Weight321.76 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Chloro-6-(4-methoxyphenyl)-2-phenylpyrimidine-5-carbonitrile CAS 320418-90-4 chemical structure

Description

The occurrence of 4-Chloro-6-(4-methoxyphenyl)-2-phenylpyrimidine-5-carbonitrile is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-Chloro-6-(4-methoxyphenyl)-2-phenylpyrimidine-5-carbonitrile (CAS 320418-90-4) is a high-purity analytical reference standard with the molecular formula C18H12ClN3O and a molecular weight of 321.76 g/mol.

The molecular framework of 4-Chloro-6-(4-methoxyphenyl)-2-phenylpyrimidine-5-carbonitrile (C18H12ClN3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-Chloro-6-(4-methoxyphenyl)-2-phenylpyrimidine-5-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC18H12ClN3O
Molecular Weight321.76 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms3

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