4-{[2-(2-Pyridinyl)-6-(trifluoromethyl)-4-pyrimidinyl]oxy}benzenecarbonitrile CAS 338754-15-7
| CAS No. | 338754-15-7 |
| Molecular Formula | C17H9F3N4O |
| Molecular Weight | 342.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-{[2-(2-Pyridinyl)-6-(trifluoromethyl)-4-pyrimidinyl]oxy}benzenecarbonitrile.
4-{[2-(2-Pyridinyl)-6-(trifluoromethyl)-4-pyrimidinyl]oxy}benzenecarbonitrile (CAS 338754-15-7) is a high-purity analytical reference standard with the molecular formula C17H9F3N4O and a molecular weight of 342.27 g/mol.
The molecular framework of 4-{[2-(2-Pyridinyl)-6-(trifluoromethyl)-4-pyrimidinyl]oxy}benzenecarbonitrile (C17H9F3N4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-{[2-(2-Pyridinyl)-6-(trifluoromethyl)-4-pyrimidinyl]oxy}benzenecarbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H9F3N4O |
| Molecular Weight | 342.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Pyridinyl Standards
- 2-(2-(2-(3-Pyridinyl)-1,3-thiazol-4-yl)-ethyl)-1H-isoindole-1,3(2H)-dione (CAS 860785-67-7)
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- 5-Methyl-2-(2-pyridinyl)-1,3-thiazol-4-yl 2,4-difluorobenzenecarboxylate (CAS 338399-07-8)
- 5-Methyl-2-(4-pyridinyl)-1,3-thiazol-4-yl 2,4-difluorobenzenecarboxylate (CAS 338398-93-9)
- 1-(4-Pyridinyl)-1-ethanone N-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]hydrazone (CAS 551921-12-1)
- 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-Thiazolidinedione (CAS 627502-58-3)
- 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy-d4]phenyl]methylene]-2,4-thiazolidinedione (CAS 1217211-89-6)
- 3-(2-Pyridinyl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid (CAS 478080-12-5)
Recommended Standards
- 2-(4-Bromo-2-(tert-butyl)phenoxy)-N-isobutylacetamide (CAS 302949-66-2)
- Ethyl 5-methyl-4-((3-(trifluoromethyl)phenyl)carbamoyl)isoxazole-3-carboxylate (CAS 338761-34-5)
- 1-(1-Methyl-2-oxopropyl)-3-[2-(trifluoromethyl)benzyl]-1H-imidazole-2,4,5(3H)-trione (CAS 338392-45-3)
- Methyl (4Z)-2-methyl-5-oxo-4-({[4-(trifluoromethoxy)phenyl]amino}methylidene)-4,5-dihydro-1H-pyrrole-3-carboxylate (CAS 338413-27-7)
- Ethyl 6-(piperazin-1-yl)nicotinate dihydrochloride (CAS 1210674-00-2)
- DL-3-Methylamphetamine hydrochloride (CAS 77083-25-1)
- 5-Methyl-6,7-dihydrobenzofuran-4(5H)-one (CAS 109307-29-1)
- 4-Hydroxy-2-methylpyrimidine (CAS 19875-04-8)
- Naproxen Impurity 16 (CAS CATO-C4X-170816)
- 2-Chloro-1-(4-(difluoromethoxy)phenyl)ethanone (CAS 1214341-01-1)
- 2-(Aminomethyl)-5-(difluoromethyl)-6-methoxypyridine-3-acetonitrile (CAS 1361798-46-0)
- 5-Methyl-6-(naphthalen-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (CAS 922186-93-4)
- 5,7-Dimethoxyindan-1-one (CAS 880-87-5)
- Semaglutide（sodium salt） (CAS CATO-C4X-222619)
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