Naproxen Impurity 16 CAS CATO-C4X-170816

Description

Compared with other compounds in its class, the molecular weight of 302.36 g/mol gives Naproxen Impurity 16 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Naproxen Impurity 16 (CAS CATO-C4X-170816), a pharmacopoeial impurity reference standard (molecular formula C18H22O4, MW 302.36 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Naproxen Impurity 16 (C18H22O4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Naproxen Impurity 16 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Why CATO?

• ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
• 130,000+ catalog items in stock, COA supplied with every batch
• Worldwide shipping with full export documentation (HS code guidance available)
• Technical support: +86 18665070610 / Nicole.chen@cato-chem.com