N-(2-chlorobenzyl)-2-(pyridin-2-yl)-6-(trifluoromethyl)pyrimidin-4-amine CAS 338754-48-6
| CAS No. | 338754-48-6 |
| Molecular Formula | C17H12ClF3N4 |
| Molecular Weight | 364.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, N-(2-chlorobenzyl)-2-(pyridin-2-yl)-6-(trifluoromethyl)pyrimidin-4-amine (C17H12ClF3N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 364.75 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
N-(2-chlorobenzyl)-2-(pyridin-2-yl)-6-(trifluoromethyl)pyrimidin-4-amine (CAS 338754-48-6) is a high-purity analytical reference standard with the molecular formula C17H12ClF3N4 and a molecular weight of 364.75 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(2-chlorobenzyl)-2-(pyridin-2-yl)-6-(trifluoromethyl)pyrimidin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H12ClF3N4 |
| Molecular Weight | 364.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related N Standards
- N-(4-Chlorobenzyl)-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine (CAS 338754-27-1)
- 1-(2-Chlorobenzyl)-6-(pyridin-3-yl)-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 929974-31-2)
- 1-(4-Chlorobenzyl)-5-(3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl)pyridin-2(1H)-one (CAS 477858-10-9)
- 1-((2-Chlorobenzyl)oxy)-2-(4-methoxyphenyl)-1H-benzo[d]imidazole (CAS 339009-73-3)
- N-(2-Chlorobenzyl)-5-oxo-4-(thiophen-2-ylmethyl)morpholine-3-carboxamide (CAS 1421445-11-5)
- 2-(1-(4-Chlorobenzyl)-2-oxo-1,2-dihydropyridine-3-carbonyl)-N-ethylhydrazine-1-carbothioamide (CAS 400074-95-5)
- 5-(4-Chlorobenzyl)-6-(((3-(dimethylamino)propyl)imino)methyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 31349-12-9)
- 2-((3-Chlorobenzyl)thio)-3-ethyl-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one (CAS 577988-96-6)
Recommended Standards
- 4-Chloro-6-methyl-2-phenyl-5-(3-(trifluoromethyl)phenoxy)pyrimidine (CAS 680217-69-0)
- 1-Acetyl-N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperidine-4-carbohydrazide (CAS 439094-42-5)
- N-(6-Chloro-4-(trifluoromethyl)pyridin-2-yl)-4,N-dimethylbenzenesulfonamide (CAS 1311280-33-7)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[(1E)-(methoxyamino)methylidene]piperidine-4-carboxamide (CAS 303144-37-8)
- 2',3'-Dihydrospiro[cyclohexane-1,1'-inden]-3'-amine (CAS 873400-44-3)
- (R)-Benzyl 3-((methylsulfonyl)oxy)pyrrolidine-1-carboxylate (CAS 122536-68-9)
- 1-Benzyl-4-(4-methylphenoxy)phthalazine (CAS 338404-27-6)
- Methyl 2,5-dichloro-4-methylphenylacetate (CAS 1803836-89-6)
- Bisoprolol EP Impurity G HCl (CAS CATO-C4X-124750)
- N-((4-ethoxyphenyl)sulfonyl)-N-phenylglycine (CAS 432012-21-0)
- 2-(1h-Imidazol-1-yl)cyclohexane-1-carboxylic acid (CAS 1341937-96-9)
- N-(2,3-dimethylphenyl)-2-((4-methyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 329080-09-3)
- 2-(2-Bromoethoxy)-1,4-dichlorobenzene (CAS 85262-50-6)
- Semaglutide Impurity 1(OtBu-Ste-D-γGlu(OtBu)-AEEA-AEEA-OH) (CAS CATO-C4X-22261)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com