(E)-6-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-((4-(dimethylamino)benzylidene)amino)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carbonitrile CAS 338761-72-1
| CAS No. | 338761-72-1 |
| Molecular Formula | C23H19ClF3N5S |
| Molecular Weight | 489.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 489.94 g/mol gives (E)-6-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-((4-(dimethylamino)benzylidene)amino)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(E)-6-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-((4-(dimethylamino)benzylidene)amino)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carbonitrile (CAS 338761-72-1) is a high-purity analytical reference standard with the molecular formula C23H19ClF3N5S and a molecular weight of 489.94 g/mol.
(E)-6-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-((4-(dimethylamino)benzylidene)amino)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carbonitrile (C23H19ClF3N5S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H19ClF3N5S |
| Molecular Weight | 489.94 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related E Standards
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Recommended Standards
- (E)-{[4-(4-chlorophenyl)-7-thia-2,5-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,5-trien-3-yl]methylidene}({[3-(trifluoromethyl)phenyl]methoxy})amine (CAS 861212-76-2)
- 2'-[4-(3-Chlorothiophen-2-yl)-1,3-thiazol-2-yl]-2-(2,4-difluorophenyl)-5,5'-dimethyl-2H,2'H-[3,4'-bipyrazole]-3'-ol (CAS 1007030-99-0)
- Vemurafenib (CAS 918504-65-1)
- LY3295668 (CAS 1919888-06-4)
- Ethyl 2-(benzamidomethyl)-3-oxobutanoate (CAS 69396-18-5)
- 2-Methylisoxazol-3(2H)-one (CAS 26347-18-2)
- 5,8-Dihydroxynaphthalene-1,4(4aH,8aH)-dione (CAS 887574-80-3)
- Tert-butyl 7-(trifluoromethyl)-2,5-diazabicyclo[4.1.0]Heptane-2-carboxylate (CAS 1235439-95-8)
- Berberine Impurity 15 Chloride (CAS 1186107-72-1)
- Sodium 2-(6-(difluoromethyl)pyridin-2-yl)acetate (CAS 2197057-20-6)
- 3,3-Difluorocyclopentan-1-amine (CAS 939525-61-8)
- 8-Bromo-1,11-dihydro-2H-pyrimido[4,5-a]carbazol-2-one (CAS 1499223-18-5)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-6-methylpyrimidin-4-ol (CAS 907986-71-4)
- (His32,Leu34)-Neuropeptide Y (32-36) (CAS 168916-68-5)
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