2-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indol-3-yl)-N-(4-methoxyphenyl)-2-oxoacetamide CAS 338770-03-9
| CAS No. | 338770-03-9 |
| Molecular Formula | C23H15ClF3N3O3 |
| Molecular Weight | 473.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 473.83 g/mol gives 2-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indol-3-yl)-N-(4-methoxyphenyl)-2-oxoacetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indol-3-yl)-N-(4-methoxyphenyl)-2-oxoacetamide (CAS 338770-03-9), molecular formula C23H15ClF3N3O3 and molecular weight 473.83 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indol-3-yl)-N-(4-methoxyphenyl)-2-oxoacetamide (C23H15ClF3N3O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H15ClF3N3O3 |
| Molecular Weight | 473.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- N-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-5-methyl-3-phenylisoxazole-4-carboxamide (CAS 1023539-12-9)
- Ethyl 3-((1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrole)-2-sulfonamido)benzoate (CAS 338407-13-9)
- (2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-1-(3,4-dimethoxyphenethyl)-1H-imidazol-5-yl)methanol (CAS 338422-54-1)
- N-{[5-chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl}-N-(4-methoxyphenyl)-4-methylbenzene-1-sulfonamide (CAS 955962-95-5)
- 5-Chloro-2-methoxybenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144036-95-2)
- (2E)-1-{3-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-3-[(4-phenoxyphenyl)amino]prop-2-en-1-one (CAS 478039-76-8)
- 4-(3-Chloro-2-fluoroanilino)-7-methoxy-6-[[1-(N-methylcarbamoylmethyl)piperidin-4-yl]oxy]quinazoline (CAS 848942-61-0)
- N-(3-chloro-4-methylphenyl)-2-(2-ethoxy-4-formyl-6-iodophenoxy)acetamide (CAS 553630-07-2)
Recommended Standards
- N-(2-Methyl-4-nitronaphthalen-1-yl)acetamide (CAS 13615-36-6)
- 7-(Benzo[d][1,3]dioxol-5-yl)-2-(3-(2-chloro-6-fluorophenyl)-4-methylisoxazol-5-yl)-[1,2,4]triazolo[1,5-a]pyridine-8-carbonitrile (CAS 860650-23-3)
- 2-(Bromomethyl)-5-(difluoromethyl)-3,4-diiodopyridine (CAS 1805158-89-7)
- Rimonabant-d10 (CAS 929221-88-5)
- 6-Oxo-1-(2-oxo-2-((3,4,5-trimethoxyphenyl)amino)ethyl)-1,6-dihydropyridine-3-carboxylic acid (CAS 1432437-22-3)
- N-Dechloroethyl Cyclophosphamide-d4 (CAS 1346600-68-7)
- Octyl 5-(Diethylamino)-2-(phenylsulfonyl)-2,4-pentadienoate (CAS 98835-90-6)
- 3-Amino-4-methylheptanoic acid (CAS 204191-41-3)
- 6-phenyl-3,7-dioxabicyclo[4.1.0]heptane (CAS 1934507-71-7)
- 1-(1,2-Diaminopropan-2-yl)cyclopropanecarboxylic acid (CAS 915867-73-1)
- (3-Fluoro-5-(isobutylcarbamoyl)phenyl)boronic acid (CAS 2096338-93-9)
- 2-((1s,2s,3s)-2-Amino-3-(trifluoromethyl)cyclopropyl)acetic acid (CAS 1305711-14-1)
- 5,5-Dimethyl-2-(4-nitrophenyl)-4,5-dihydrooxazole (CAS 10316-85-5)
- Peptide Impurity 40 (CAS CATO-CPTD788840)
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