5-[(1E)-1-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]hydrazin-1-ylidene}ethyl]-3-(4-fluorophenyl)-2,1-benzoxazole CAS 338772-44-4
| CAS No. | 338772-44-4 |
| Molecular Formula | C21H13ClF4N4O |
| Molecular Weight | 448.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5-[(1E)-1-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]hydrazin-1-ylidene}ethyl]-3-(4-fluorophenyl)-2,1-benzoxazole (CAS 338772-44-4) is a high-purity analytical reference standard with the molecular formula C21H13ClF4N4O and a molecular weight of 448.80 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 5-[(1E)-1-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]hydrazin-1-ylidene}ethyl]-3-(4-fluorophenyl)-2,1-benzoxazole is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 448.80 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H13ClF4N4O |
| Molecular Weight | 448.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related E Standards
- 1-{4-[(1Z)-1-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]hydrazin-1-ylidene}ethyl]phenyl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (CAS 321432-43-3)
- 2-((2-Chloro-6-fluorobenzyl)thio)-5-(1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazol-5-yl)-1,3,4-oxadiazole (CAS 339103-41-2)
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Recommended Standards
- Chlorobis(dimethylglyoximato)[4-(dimethylamino)pyridine]cobalt(III) (CAS 483979-48-2)
- Ethyl N-[(2E)-2-({4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}methylidene)-3-oxobutanoyl]carbamate (CAS 339103-90-1)
- Dipentamethylenethiuram hexasulfide(DPTT) (CAS 971-15-3)
- (E)-[(4-chlorophenyl)methoxy][4-(6-chloropyridin-3-yl)-3-[(6-chloropyridin-3-yl)methyl]butan-2-ylidene]amine 5W-0864 866040-63-3 (CAS 866040-63-3)
- tert-Butyl (4-(2-aminoacetamido)cyclohexyl)(isopropyl)carbamate (CAS 1353973-09-7)
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- 4-Cyano-6-(difluoromethyl)-5-nitropicolinoyl chloride (CAS 1805489-36-4)
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- 1-(propan-2-yl)-1,2,3,6-tetrahydropyridin-4-yl trifluoromethanesulfonate (CAS 1603833-91-5)
- 2-(3-Chlorophenyl)-4-(thiophen-2-yl)-2,3-dihydrobenzo[b][1,4]thiazepine (CAS 866136-88-1)
- 3-Formyl-4-hydroxypicolinic acid (CAS 1289035-71-7)
- (Tyr?)-C-Peptide (dog) (CAS 101135-67-5)
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