1-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-2,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indol-4-one CAS 1023498-80-7
| CAS No. | 1023498-80-7 |
| Molecular Formula | C23H20ClF3N2O2 |
| Molecular Weight | 448.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-2,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indol-4-one (C23H20ClF3N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-2,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indol-4-one (CAS 1023498-80-7) is a high-purity analytical reference standard with the molecular formula C23H20ClF3N2O2 and a molecular weight of 448.87 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-2,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indol-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H20ClF3N2O2 |
| Molecular Weight | 448.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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