N-(2,5-Dichlorophenyl)-6-hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide CAS 338774-72-4
| CAS No. | 338774-72-4 |
| Molecular Formula | C12H9Cl2N3O3 |
| Molecular Weight | 314.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(2,5-Dichlorophenyl)-6-hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-(2,5-Dichlorophenyl)-6-hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide (CAS 338774-72-4) is a high-purity analytical reference standard with the molecular formula C12H9Cl2N3O3 and a molecular weight of 314.12 g/mol.
The molecular framework of N-(2,5-Dichlorophenyl)-6-hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide (C12H9Cl2N3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(2,5-Dichlorophenyl)-6-hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H9Cl2N3O3 |
| Molecular Weight | 314.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- 6-Acetyl-2-(3,5-dichlorophenyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione (CAS 477854-32-3)
- N-(2,3-Dichlorophenyl)-6-hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide (CAS 338774-73-5)
- N-(2,4-Dichlorophenyl)-6-hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyrimidinecarboxamide (CAS 861208-48-2)
- N-(3,4-Dichlorophenyl)-6-hydroxy-1-methyl-2-oxo-1,2-dihydropyrimidine-4-carboxamide (CAS 861208-54-0)
- 5-(2,4-Dichlorophenyl)-N-(2-hydroxyethyl)-2-methylfuran-3-carboxamide (CAS 875286-75-2)
- Ethyl 3-(2,4-dichlorophenyl)-2-(1,2-oxazol-5-yl)propanoate (CAS 672949-13-2)
- Methyl 3-(2,6-dichlorophenyl)-5-isopropylisoxazole-4-carboxylate (CAS 278597-28-7)
- 2-(3,4-Dichlorophenyl)naphtho[1,2-d]oxazole (CAS 1415985-98-6)
Recommended Standards
- VO5437P1A2 32861-85-1 Chlomethoxyfen [BSI:ISO] Chlormethoxynil Chlomethoxynil 2,4-Dichlorophenyl 3-methoxy-4-nitrophenyl ether Ether, (2,4-dichlorophenyl) (3-methoxy-4-nitrophenyl) X-52 BRN 2158908 CCRIS 7157 Chlomethoxyfen 4-(2,4-Dichlorophenoxy)-2-methoxy-1-nitrobenzene 5-(2,4-Dichlorophenoxy)-2-nitroanisole 2,4-Dichlorophenyl 3'-methoxy-4'-nitrophenyl ether Diphenex EINECS 251-266-1 Ekkusagoni UNII-VO5437P1A2 (CAS 32861-85-1)
- Ethyl 4-(3,4-dichloro-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoate (CAS 65833-17-2)
- Resmetirom Impurity 37 (CAS CATO-C4X-291237)
- 3-Bromo-4-(2-(cyclopropylamino)-2-oxoethoxy)benzoic acid (CAS 1050911-41-5)
- 4-(Trifluoromethyl)benzenesulfonic acid (CAS 109787-11-3)
- (1R,2R)-2-(1H-pyrazol-1-yl)cyclopentan-1-ol (CAS 1807940-02-8)
- Thiophene-3,4-diamine dihydrobromide (CAS 169698-12-8)
- 2-Amino-5-fluoro-N,N-dimethylbenzamide (CAS 1094352-35-8)
- Relugolix Impurity 170 (CAS CATO-C4X-2429170)
- 3-(3-Methoxyphenyl)-1-oxoisochromane-4-carboxylic acid (CAS 400751-55-5)
- 7-bromo-5-fluoro-1,2,3,4-tetrahydroquinoline hydrochloride (CAS 1432681-93-0)
- Samarium(III) acetate hydrate (CAS 100587-91-5)
- 1-(p-Tolyl)-1H-pyrazol-4-amine (CAS 90839-86-4)
- C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 127869-51-6)
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