5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(2,6-dichlorophenyl)-3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2]oxazole-4,6-dione CAS 338775-03-4
| CAS No. | 338775-03-4 |
| Molecular Formula | C18H10Cl3F3N4O3 |
| Molecular Weight | 493.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(2,6-dichlorophenyl)-3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2]oxazole-4,6-dione.
5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(2,6-dichlorophenyl)-3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2]oxazole-4,6-dione (CAS 338775-03-4), molecular formula C18H10Cl3F3N4O3 and molecular weight 493.65 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C18H10Cl3F3N4O3, 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(2,6-dichlorophenyl)-3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2]oxazole-4,6-dione contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 493.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(2,6-dichlorophenyl)-3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2]oxazole-4,6-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H10Cl3F3N4O3 |
| Molecular Weight | 493.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related chloro Standards
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Recommended Standards
- (6R,9aR)-1-(3-(1H-indol-3-yl)propanoyl)-6-butyl-8-(piperidin-4-ylmethyl)hexahydro-4H-pyrazino[1,2-a]pyrimidine-4,7(6H)-dione (CAS CATO-C3D-262711)
- (1R)-2'-(Dicyclohexylphosphanyl)-N,N-dimethyl-[1,1'-binaphthalen]-2-amine (CAS 255882-15-6)
- Ethyl 2-(4-(dimethylamino)benzylidene)-7-methyl-5-(4-(methylthio)phenyl)-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 351516-96-6)
- 2′-(Dicyclohexylphosphino)-N,N-dimethyl[1,1′-binaphthalen]-2-amine (CAS 255835-81-5)
- 4-Chloro-3-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzonitrile (CAS 883898-94-0)
- 4,4-Diphenylcyclohexan-1-ol (CAS 42420-85-9)
- 5-cyclopropyl-2-(4-fluorophenyl)-6-(methylsulfonamido)benzofuran-3-carboxylic acid (CAS 691857-54-2)
- Diflubenzuron-d4 (CAS 1219795-45-5)
- 3,5-Dioxocyclohexanecarboxylicacid (CAS 42858-60-6)
- 2-Chloro-6-methylbenzotrifluoride 1-Chloro-3-methyl-2-(trifluoromethyl)benzene 112641-25-5 (CAS 112641-25-5)
- 2-(6-Chloropyridin-3-yl)benzo[d]oxazole (CAS 54628-03-4)
- Vitamin A Impurity 28 (CAS CATO-C4X-218728)
- (3aS,8aR)-2-(6-Benzhydrylpyridin-2-yl)-4,8b-dihydro-3aH-indeno[1,2-d][1,3]oxazole (CAS 2757083-52-4)
- Semaglutide Impurity 155 (x TFA Salt) (CAS CATO-C4X-2226155)
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