3-(2-Chloro-6-fluorophenyl)-N-(2-hydroxy-5-(piperidin-1-ylsulfonyl)phenyl)-5-methylisoxazole-4-carboxamide CAS 748146-36-3
| CAS No. | 748146-36-3 |
| Molecular Formula | C22H21ClFN3O5S |
| Molecular Weight | 493.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(2-Chloro-6-fluorophenyl)-N-(2-hydroxy-5-(piperidin-1-ylsulfonyl)phenyl)-5-methylisoxazole-4-carboxamide.
CATO supplies 3-(2-Chloro-6-fluorophenyl)-N-(2-hydroxy-5-(piperidin-1-ylsulfonyl)phenyl)-5-methylisoxazole-4-carboxamide (CAS 748146-36-3), a certified reference material (molecular formula C22H21ClFN3O5S, MW 493.94 g/mol) for analytical method development and quality control.
Structurally, 3-(2-Chloro-6-fluorophenyl)-N-(2-hydroxy-5-(piperidin-1-ylsulfonyl)phenyl)-5-methylisoxazole-4-carboxamide (C22H21ClFN3O5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 493.94 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(2-Chloro-6-fluorophenyl)-N-(2-hydroxy-5-(piperidin-1-ylsulfonyl)phenyl)-5-methylisoxazole-4-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H21ClFN3O5S |
| Molecular Weight | 493.94 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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- N-(2-Chloro-4,6-dimethylphenyl)-2-((4-(4-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618432-50-1)
- 2-Chloro-4-(cyclopentyloxy)-5-iodo-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 1618663-33-4)
Recommended Standards
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- 4,6-Dibromo-2-(3-iodophenyl)benzo[d]oxazol-5-amine (CAS 586996-09-0)
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- 9-Chloro-6-methoxy-2-(trifluoromethyl)acridine (CAS 811432-17-4)
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