4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}-N-(4-methoxyphenyl)benzene-1-sulfonamide CAS 338775-28-3
| CAS No. | 338775-28-3 |
| Molecular Formula | C19H14ClF3N2O4S |
| Molecular Weight | 458.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}-N-(4-methoxyphenyl)benzene-1-sulfonamide (CAS 338775-28-3), molecular formula C19H14ClF3N2O4S and molecular weight 458.84 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C19H14ClF3N2O4S, 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}-N-(4-methoxyphenyl)benzene-1-sulfonamide contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 458.84 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}-N-(4-methoxyphenyl)benzene-1-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H14ClF3N2O4S |
| Molecular Weight | 458.84 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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