Etoricoxib Impurity 33 CAS 1817735-82-2
| CAS No. | 1817735-82-2 |
| Molecular Formula | C25H20ClN3O3S |
| Molecular Weight | 477.96 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Etoricoxib Impurity 33 (CAS 1817735-82-2), a pharmacopoeial impurity reference standard (molecular formula C25H20ClN3O3S, MW 477.96 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C25H20ClN3O3S, Etoricoxib Impurity 33 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 477.96 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C25H20ClN3O3S |
| Molecular Weight | 477.96 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Etoricoxib Standards
- Etoricoxib Impurity 21 (CAS CATO-C4X-108021)
- Etoricoxib impurity 55 (CAS 646459-40-7)
- Etoricoxib Impurity 92 (CAS CATO-C4X-108092)
- Etoricoxib impurity 56 (CAS 646459-51-0)
- Etoricoxib Impurity 12 (CAS CATO-C4X-108012)
- Etoricoxib impurity 01 (CAS 646459-49-6)
- Etoricoxib impurity 53 (CAS 646459-43-0)
- Etoricoxib impurity 54 (CAS 646459-47-4)
Recommended Standards
- 2-((5-(4-Chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(3-(furan-2-yl)allylidene)acetohydrazide (CAS 307975-51-5)
- Trelagliptin Impurity 49 (CAS CATO-C4X-104649)
- 4-(3-((5-(4-Chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acrylamido)benzamide (CAS 477331-52-5)
- Mosapride Impurity 61 (CAS CATO-C4X-104461)
- Diclofenac acid Impurity 52 (CAS CATO-C4X-105152)
- Cinacalcet Impurity 26 (CAS 1201-74-7)
- Upadacitinib Impurity 7 (CAS CATO-C4X-24057)
- 4-Iodo-5-methoxy-1H-indazole (CAS 1352397-29-5)
- 4-Bromo-5-(difluoromethyl)-6-iodonicotinoyl chloride (CAS 1807027-71-9)
- (3E)-3-[(3-Fluorophenyl)methylidene]-3,4-dihydro-2H-1-benzopyran-4-one (CAS 207442-39-5)
- Ethyl 1-amino-4,4-difluorocyclohexane-1-carboxylate (CAS 1393637-94-9)
- 2-Methyl-4-(thietan-3-ylamino)hexan-1-ol (CAS 1865105-48-1)
- 2-(Allylamino)-N-(o-tolyl)propanamide (CAS 54749-85-8)
- [Formaldehyde Schiff-base]-Semaglutide Impurity 136 X TFA Salt (CAS CATO-C4X-2226136)
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