N-(2,4-dichlorophenyl)-2,2-difluoro-2-(3-(trifluoromethyl)phenoxy)acetamide CAS 338792-06-6
| CAS No. | 338792-06-6 |
| Molecular Formula | C15H8Cl2F5NO2 |
| Molecular Weight | 400.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(2,4-dichlorophenyl)-2,2-difluoro-2-(3-(trifluoromethyl)phenoxy)acetamide.
CATO supplies N-(2,4-dichlorophenyl)-2,2-difluoro-2-(3-(trifluoromethyl)phenoxy)acetamide (CAS 338792-06-6), a certified reference material (molecular formula C15H8Cl2F5NO2, MW 400.13 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-(2,4-dichlorophenyl)-2,2-difluoro-2-(3-(trifluoromethyl)phenoxy)acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 400.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H8Cl2F5NO2 |
| Molecular Weight | 400.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- N-(2,6-dichlorophenyl)-2,2-difluoro-2-(3-(trifluoromethyl)phenoxy)acetamide (CAS 338792-20-4)
- N-(3,4-dichlorophenyl)-2,2-difluoro-2-(3-(trifluoromethyl)phenoxy)acetamide (CAS 338792-05-5)
- 4-(2,4-Dichlorophenyl)-8-(trifluoromethoxy)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline (CAS 342405-95-2)
- 1-[(2,4-Dichlorophenyl)methoxy]-2-(4-methoxyphenyl)-1H-imidazo[4,5-b]pyridine (CAS 339027-99-5)
- 4-(3-(2,4-Dichlorophenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-yl)morpholine (CAS 338977-91-6)
- 4-(3-(3,4-Dichlorophenyl)-[1,2,4]triazolo[4,3-c]quinazolin-5-yl)morpholine (CAS 338977-95-0)
- 2-(3,4-Dichlorophenyl)-6-(3-fluorobenzyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine (CAS 477850-29-6)
- 5-(2,6-Dichlorophenyl)-2-(phenylthio)-6H-pyrimido[1,6-b]pyridazin-6-one (CAS 209409-98-3)
Recommended Standards
- 4-[3-Chloro-7-(chlorodifluoromethyl)-5-methylpyrazolo[1,5-a]pyrimidin-2-yl]-1-methyl-5-(trifluoromethyl)-1H-pyrazole (CAS 956781-26-3)
- 2,5-Dibromo-n-(3-(dimethylamino)propyl)benzenesulfonamide (CAS 919968-98-2)
- 1-(4-Bromophenyl)-3-((4-bromophenyl)thio)propan-1-one (CAS 882749-13-5)
- 5-Methyl-3-(perfluorohexyl)-1H-pyrazole (CAS 129257-23-4)
- 2-Ethynyl-5-fluoro-4-methoxypyrimidine (CAS 1330044-12-6)
- 5-Methoxy-2-methylpyridin-3-amine (CAS 1104455-29-9)
- N-Cyclohexyl-3-methyl-2,3-dihydro-1H-inden-1-amine (CAS 1220039-40-6)
- Atrasentan Impurity 60 (CAS 1072963-94-0)
- 6,7-Dichloro-1H-indole-2-carboxylic acid (CAS 383132-13-6)
- 1-Phenyl-3-(o-tolyl)propan-1-one (CAS 84839-91-8)
- N-(3-methoxybenzyl)cyclopropanamine hydrochloride (CAS 1050419-13-0)
- 2'-O-Me-C(Bz) Phosphoramidite (CAS 110764-78-8)
- 1-(2,4,6-Tribromophenyl)thiourea (CAS 5337-47-3)
- Semaglutide impurity 247 (CAS CATO-C4X-2226247)
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