1-(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}butyl)-4,4-dimethylpiperidine-2,6-dione CAS 338792-97-5
| CAS No. | 338792-97-5 |
| Molecular Formula | C21H28ClF3N4O2 |
| Molecular Weight | 460.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}butyl)-4,4-dimethylpiperidine-2,6-dione is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}butyl)-4,4-dimethylpiperidine-2,6-dione (CAS 338792-97-5) is a high-purity analytical reference standard with the molecular formula C21H28ClF3N4O2 and a molecular weight of 460.92 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 1-(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}butyl)-4,4-dimethylpiperidine-2,6-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 460.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}butyl)-4,4-dimethylpiperidine-2,6-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H28ClF3N4O2 |
| Molecular Weight | 460.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
- N-(3-Acetylphenyl)-2-chloro-5-(N-(4-fluorophenyl)-N-methylsulfamoyl)benzamide (CAS 865279-64-7)
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- Methyl 5-(4-chlorophenyl)-4,6-dioxo-1,3-diphenyl-octahydropyrrolo[3,4-c]pyrrole-1-carboxylate (CAS 317821-76-4)
- Gefitinib impurity 62 (CAS CATO-C4X-111762)
- (4-(Ethoxycarbonyl)cyclohex-1-en-1-yl)boronic acid (CAS 1443112-50-2)
- Ethyl 5-formyl-3,4-dimethyl-1H-pyrrole-2-carboxylate (CAS 4391-99-5)
- 6-Ethyl-3-oxa-1-azaspiro[4.5]dec-1-en-2-amine (CAS 1496380-69-8)
- 4-Phenyl-2,3-dihydro-1H-inden-1-one (CAS 78383-17-2)
- 3-(4-Bromophenyl)-3-acetamidopropanoic acid (CAS 886363-73-1)
- Ethyl 1-(chloroacetyl)piperidine-2-carboxylate (CAS 1008946-66-4)
- 1,3-Diphenyl-1,8-dihydrodibenzo[b,f]pyrazolo[3,4-d]azepine (CAS 85008-87-3)
- 2-(2-Butyramido-4-phenylthiazol-5-yl)acetic acid (CAS 1181254-88-5)
- 5-Amino-1-(2-isobutoxyethyl)pyridin-2(1h)-one (CAS 1094868-29-7)
- Prolactin-Releasing Peptide (12-31), rat (CAS 222988-10-5)
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