Gefitinib impurity 62 CAS CATO-C4X-111762
| CAS No. | CATO-C4X-111762 |
| Molecular Formula | C23H26ClFN4O3 |
| Molecular Weight | 460.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 460.93 g/mol gives Gefitinib impurity 62 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Gefitinib impurity 62 (CAS CATO-C4X-111762), a pharmacopoeial impurity reference standard (molecular formula C23H26ClFN4O3, MW 460.93 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Gefitinib impurity 62 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 460.93 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Gefitinib impurity 62 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H26ClFN4O3 |
| Molecular Weight | 460.93 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Gefitinib Standards
Recommended Standards
- 5-[2-[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]ethyl]-4-chloro-2-nitro-benzeneacetic Acid (CAS 160384-40-7)
- Ziprasidone Impurity 65 (CAS CATO-C4X-124065)
- 1-(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}butyl)-4,4-dimethylpiperidine-2,6-dione (CAS 338792-97-5)
- (4-Bromophenyl)(5,7-dibromobenzofuran-2-yl)methanol (CAS 83806-76-2)
- Peramivir Impurity 82 (CAS CATO-C4X-183382)
- Regorafenib Impurity 60 (CAS CATO-C4X-104760)
- Indapamide Impurity 46 (CAS CATO-C4X-140046)
- 4,6-Dichloro-2-methylpyrimidine-5-carbaldehyde (CAS 14160-91-9)
- Iodoacetyl Chloride (CAS 38020-81-4)
- 2-Hydroxy-6-methylpyrimidine-4-carboxamide (CAS 88394-12-1)
- 6-Bromo-3-((tert-butoxycarbonyl)amino)-5-(trifluoromethyl)picolinic acid (CAS 2761296-43-7)
- 2-(tert-Butyl)-6-nitrobenzo[d]oxazole (CAS 116549-24-7)
- UNC 0642 (CAS 1481677-78-4)
- Semaglutide Impurity 140 (CAS CATO-C4X-2226140)
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