8-Chloro-3-(pyridin-4-yl)-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine CAS 338795-36-1
| CAS No. | 338795-36-1 |
| Molecular Formula | C12H6ClF3N4 |
| Molecular Weight | 298.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 8-Chloro-3-(pyridin-4-yl)-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine (C12H6ClF3N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 298.65 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
8-Chloro-3-(pyridin-4-yl)-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine (CAS 338795-36-1), molecular formula C12H6ClF3N4 and molecular weight 298.65 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H6ClF3N4 |
| Molecular Weight | 298.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 6-Chloro-3-(2-(trifluoromethyl)phenyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1094452-66-0)
- 4-Chloro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 1096951-17-5)
- 4-Chloro-1-(4-(trifluoromethyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 1269703-41-4)
- 2-Chloro-4-(morpholin-4-yl)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine (CAS 1283693-68-4)
- 6-Chloro-3-(4-(trifluoromethyl)phenyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 175204-95-2)
- 7-Chloro-2-(3-(trifluoromethyl)phenyl)-2H-pyrazolo[3,4-d]pyridazine (CAS 1956379-80-8)
- 2-[8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]pyridine (CAS 339099-44-4)
- 3-[8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]pyridine (CAS 339099-70-6)
Recommended Standards
- 7-Chloro-5-(3-(trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 75175-85-8)
- Ethyl N-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-N-methoxycarbamate (CAS 338422-74-5)
- 6-(3-Chlorophenyl)-2-hydroxy-4-(trifluoromethyl)nicotinonitrile (CAS 338749-71-6)
- 2-(8-chloro-1-naphthyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2454397-84-1)
- 4-Bromo-5-isopropyl-2-methylphenol (CAS 121665-99-4)
- 5-Bromo-2-chloro-3-iodopyridin-4-amine (CAS 2173992-38-4)
- 3-Amino-3-(2,5-difluorophenyl)propanoic acid (CAS 773122-52-4)
- 2-((4-Amino-5-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetic acid (CAS 573707-08-1)
- 1,2,3-Trimethyl-5-(pyrrolidin-2-yl)-1H-indole (CAS 1507816-32-1)
- 2-(4-Fluorophenoxy)-N-((1-(4-fluorophenyl)cyclopropyl)methyl)acetamide (CAS 1049435-91-7)
- tert-Butyl (S)-3-oxohexahydroimidazo[1,5-a]pyrazine-7(1H)-carboxylate (CAS 1808248-64-7)
- Methyl 2-(2,3-dichlorophenyl)-2-(methylamino)acetate (CAS 1218341-19-5)
- 2,3-Dihydro-1H-inden-1-one oxime (CAS 3349-60-8)
- Semaglutide impurity 25 (CAS CATO-C4X-222625)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com