2,4-bis(trifluoromethyl)-9-[3-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-a][1,8]naphthyridine CAS 338962-21-3
| CAS No. | 338962-21-3 |
| Molecular Formula | C18H7F9N4 |
| Molecular Weight | 450.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 450.26 g/mol gives 2,4-bis(trifluoromethyl)-9-[3-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-a][1,8]naphthyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2,4-bis(trifluoromethyl)-9-[3-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-a][1,8]naphthyridine (CAS 338962-21-3), molecular formula C18H7F9N4 and molecular weight 450.26 g/mol, is a CATO reference standard with documented purity and traceability.
2,4-bis(trifluoromethyl)-9-[3-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-a][1,8]naphthyridine (C18H7F9N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H7F9N4 |
| Molecular Weight | 450.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related bis Standards
- 3,5-Bis(trifluoromethyl)-1-(nonafluoropentanoyl)pyrazole (CAS 231285-85-1)
- 3-[3-(Trifluoromethyl)phenyl]-2-{[3-(trifluoromethyl)phenyl]sulfanyl}quinoline (CAS 339103-28-5)
- 3-((3,5-Bis(trifluoromethyl)phenyl)amino)-4-(((1R,2R)-2-(dimethylamino)cyclohexyl)amino)cyclobut-3-ene-1,2-dione (CAS 1211565-07-9)
- 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(1S,2S)-2-(dimethylamino)cyclohexyl]amino]-3-cyclobutene-1,2-dione (CAS 1263205-96-4)
- 2-[5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-2-[4-(trifluoromethyl)phenyl]acetonitrile (CAS 478049-39-7)
- 8-Benzyl-4-[4-(trifluoromethyl)benzoyl]-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326810-09-6)
- 8-Benzyl-4-[3-(trifluoromethyl)benzoyl]-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326811-62-4)
- 2,4-Bis(trifluoromethyl)-7-[(E)-2-{[3-(trifluoromethyl)phenyl]methylidene}hydrazin-1-yl]-1,8-naphthyridine (CAS 338962-17-7)
Recommended Standards
- 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-[(4-chlorophenyl)sulfanyl]pyrrolidine-2,5-dione (CAS 339110-57-5)
- Ethyl 2-amino-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-(3-chlorothiophen-2-yl)-1H-pyrrole-3-carboxylate (CAS 341966-09-4)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[(4-chlorophenyl)methyl]-1H-pyrrole-2-sulfonamide (CAS 338406-72-7)
- tert-Butyl 5,7-dichloro-6-(((trifluoromethyl)sulfonyl)oxy)-3,4-dihydroisoquinoline-2(1H)-carboxylate (CAS 851784-78-6)
- 4-[(4-Chlorophenyl)methanesulfonyl]-2-[(4-methylphenyl)methanesulfonyl]-5,6,7,8-tetrahydroquinazoline (CAS 478049-58-0)
- 1,1'-(Dihydropyrimidine-1,3(2H,4H)-diyl)bis(hexadecan-1-one) (CAS 32644-62-5)
- S,S,S,S,S-Trandolapril HCl (CAS 80828-32-6)
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- 2-Fluoro-[1,1'-biphenyl]-4-carbaldehyde (CAS 57592-43-5)
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- Scopolamine Methyl Nitrate (CAS 6106-46-3)
- O-((5-chloro-1,2,3-thiadiazol-4-yl)methyl)hydroxylamine hydrochloride (CAS 318288-80-1)
- endo-Ser39-Tirzepatide (CAS CATO-CPTD788935)
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