1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-[(4-chlorophenyl)sulfanyl]pyrrolidine-2,5-dione CAS 339110-57-5
| CAS No. | 339110-57-5 |
| Molecular Formula | C17H12Cl2F3N3O2S |
| Molecular Weight | 450.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 450.26 g/mol gives 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-[(4-chlorophenyl)sulfanyl]pyrrolidine-2,5-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-[(4-chlorophenyl)sulfanyl]pyrrolidine-2,5-dione (CAS 339110-57-5) is a high-purity analytical reference standard with the molecular formula C17H12Cl2F3N3O2S and a molecular weight of 450.26 g/mol.
The molecular framework of 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-[(4-chlorophenyl)sulfanyl]pyrrolidine-2,5-dione (C17H12Cl2F3N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-[(4-chlorophenyl)sulfanyl]pyrrolidine-2,5-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H12Cl2F3N3O2S |
| Molecular Weight | 450.26 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related chloro Standards
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[(4-chlorophenyl)methyl]-1H-pyrrole-2-sulfonamide (CAS 338406-72-7)
- 3-(2-chloro-6-fluorophenyl)-4-[4-(4-chloro-3-nitrophenyl)-1,3-thiazol-2-yl]-5-methylisoxazole (CAS 287176-95-8)
- 1-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-((4-chlorophenyl)thio)ethan-1-one (CAS 260442-99-7)
- 4-Chloro-N-(2-((4-chloro-3-nitrophenyl)amino)-2-oxoethyl)-N-cyclohexylbenzamide (CAS 332156-36-2)
- N-(2-chloro-6-((4-isopropyl-1-methyl-7-oxabicyclo[2.2.1]heptan-2-yl)oxy)benzyl)benzenesulfonamide (CAS 1005085-57-3)
- 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-butyric acid (CAS 82103-70-6)
- 2-Chloro-N-(4-(((4-fluorophenyl)thio)methyl)phenyl)-4-(methylsulfonyl)benzamide (CAS 338398-82-6)
- 3-Chloro-N-(4-(n-(thiazol-2-yl)sulfamoyl)phenyl)benzo[b]thiophene-2-carboxamide (CAS 215778-07-7)
Recommended Standards
- 2,4-bis(trifluoromethyl)-9-[3-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-a][1,8]naphthyridine (CAS 338962-21-3)
- 2,5-Bis(bromomethyl)-1-methoxy-4-(3′,7′-dimethyloctyloxy)benzene (CAS 287919-00-0)
- Ethyl 2-amino-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-(3-chlorothiophen-2-yl)-1H-pyrrole-3-carboxylate (CAS 341966-09-4)
- N-(3-(3,4-dichlorophenyl)imidazo[1,2-a]pyridin-8-yl)-3-(trifluoromethyl)benzamide (CAS 338415-25-1)
- 4-((1H-Benzo[d]imidazol-1-yl)methyl)thiophene-2-carbaldehyde (CAS 883291-27-8)
- 2-aminothiazole-4-carbaldehyde (CAS 98020-38-3)
- 1H-Benzo[d][1,2,3]triazole-5-carbonitrile (CAS 24611-70-9)
- (3E)-1-(4-Bromophenyl)-3-{[(2,4-dichlorophenyl)methoxy]imino}propan-1-one (CAS 338976-49-1)
- 2-(4-Chloro-3-nitrophenyl)-1,3-dithiolane (CAS 852218-13-4)
- 1-Ethyl-2-methylpyrrolidin (CAS 765-79-7)
- 1',4'-Dihydro-3'H-spiro[piperidine-4,2'-quinoxalin]-3'-one dihydrochloride (CAS 1268983-14-7)
- 2-(3-Methoxyphenyl)cyclopropane-1-carboxylic acid (CAS 900254-25-3)
- Dyclonine Impurity 33 HCl (CAS CATO-C4X-188133)
- Neuropeptide Y (1-24) amide (human, rat) (CAS 131448-51-6)
Why CATO?
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