5-(2-Chloro-6-fluorobenzyl)-2-(pyridin-2-yl)pyrimidine-4,6-diamine CAS 338965-14-3
| CAS No. | 338965-14-3 |
| Molecular Formula | C16H13ClFN5 |
| Molecular Weight | 329.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 329.76 g/mol gives 5-(2-Chloro-6-fluorobenzyl)-2-(pyridin-2-yl)pyrimidine-4,6-diamine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-(2-Chloro-6-fluorobenzyl)-2-(pyridin-2-yl)pyrimidine-4,6-diamine (CAS 338965-14-3), molecular formula C16H13ClFN5 and molecular weight 329.76 g/mol, is a CATO reference standard with documented purity and traceability.
5-(2-Chloro-6-fluorobenzyl)-2-(pyridin-2-yl)pyrimidine-4,6-diamine (C16H13ClFN5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H13ClFN5 |
| Molecular Weight | 329.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Chloro Standards
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- Semaglutide impurity 61 (CAS CATO-C4X-222661)
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