Furosemide Amide Impurity CAS 4793-47-9
| CAS No. | 4793-47-9 |
| Molecular Formula | C12H12ClN3O4S |
| Molecular Weight | 329.76 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Furosemide Amide Impurity (C12H12ClN3O4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Furosemide Amide Impurity (CAS 4793-47-9, C12H12ClN3O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Furosemide Amide Impurity under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12ClN3O4S |
| Molecular Weight | 329.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Furosemide Standards
- Furosemide (CAS 54-31-9)
- Furosemide EP Impurity A (CAS 4818-59-1)
- Furosemide Impurity 55 (CAS CATO-C4X-140255)
- Furosemide Impurity N3 (CAS 22893-13-6)
- Furosemide Impurity 25 (CAS 2309462-39-1)
- Furosemide Impurity 47 (CAS CATO-C4X-140247)
- Furosemide Impurity 9 (CAS CATO-C4X-14029)
- Furosemide Impurity 23 (CAS CATO-C4X-140223)
Recommended Standards
- Epoxiconazole (CAS 133855-98-8)
- 2-(Bicyclo[2.2.1]heptan-2-yl)-N-(3-chloro-4-(difluoromethoxy)phenyl)acetamide (CAS 1005126-81-7)
- Indoxacarb Impurity 1 (CAS 133001-07-7)
- 3-Chloro-2-{[(2E)-3-phenylprop-2-en-1-yl]sulfanyl}-5-(trifluoromethyl)pyridine (CAS 321430-93-7)
- Capivasertib Impurity 1 (CAS 1143532-51-7)
- Prednisolone Impurity N6 (CAS 75448-51-0)
- Roxatidine Impurity 80 (CAS 853574-98-8)
- Methyl thietan-3-yl-D-alaninate (CAS 1867604-73-6)
- 2-Amino-5-(2-hydroxyphenyl)-1-phenyl-1H-pyrrole-3,4-dicarbonitrile (CAS 88745-14-6)
- 4-(4-tert-Butylphenoxy)-2-{[(4-methylphenyl)methyl]sulfanyl}-5,6,7,8-tetrahydroquinazoline (CAS 551921-45-0)
- Ethyl 5-chloro-2-ethoxypyridine-3-carboxylate (CAS 1310416-61-5)
- Ethyl 2-(2-imino-6-methylbenzo[d]thiazol-3(2H)-yl)acetate hydrobromide (CAS 2034155-00-3)
- N-isopropylbenzenecarboximidoyl chloride (CAS 6620-80-0)
- Tirzepatide Impurity 36 (CAS CATO-C4X-324036)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com