6-Amino-4-(4-((2-chlorobenzyl)oxy)-3-methoxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile CAS 337499-07-7
| CAS No. | 337499-07-7 |
| Molecular Formula | C22H19ClN4O3 |
| Molecular Weight | 422.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 422.86 g/mol gives 6-Amino-4-(4-((2-chlorobenzyl)oxy)-3-methoxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 6-Amino-4-(4-((2-chlorobenzyl)oxy)-3-methoxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (CAS 337499-07-7), a certified reference material (molecular formula C22H19ClN4O3, MW 422.86 g/mol) for analytical method development and quality control.
Structurally, 6-Amino-4-(4-((2-chlorobenzyl)oxy)-3-methoxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (C22H19ClN4O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 422.86 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H19ClN4O3 |
| Molecular Weight | 422.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Amino Standards
- 2-Amino-1-((3-chlorobenzylidene)amino)-N-(2-methoxyethyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide (CAS 836625-75-3)
- Ethyl 2-amino-4-(2-chloro-5-nitrophenyl)-6-(hydroxymethyl)-8-oxo-4H,8H-pyrano[3,2-b]pyran-3-carboxylate (CAS 674804-97-8)
- Ethyl 2-amino-4-(3-chloro-4-nitrophenyl)-6-(hydroxymethyl)-8-oxo-4H,8H-pyrano[3,2-b]pyran-3-carboxylate (CAS 939889-02-8)
- 4-Amino-2-[(4-chlorophenyl)amino]-5-(2,4-dichlorobenzoyl)thiophene-3-carbonitrile (CAS 338966-43-1)
- 4-Amino-2-(hexadecylthio)-6-(methylthio)pyrimidine-5-carbonitrile (CAS 922526-97-4)
- 3-Amino-4-chloro-N-(2-iodo-5-methylphenyl)benzene-1-sulfonamide (CAS 554405-05-9)
- Ethyl 4-{5-amino-7-thia-1,9-diazatetracyclo[9.2.2.0^{2,10}.0^{4,8}]pentadeca-2(10),3,5,8-tetraene-6-amido}benzoate (CAS 728003-27-8)
- Ethyl 6-amino-5-cyano-4-(4-methoxyphenyl)-2-((phenylthio)methyl)-4H-pyran-3-carboxylate (CAS 478079-20-8)
Recommended Standards
- 4-Chloro-N-(2-{11,15-dioxa-16-azatetracyclo[8.7.0.0^{2,7}.0^{13,17}]heptadeca-1(10),2(7),3,5,8-pentaen-16-yl}-2-oxoethyl)benzamide (CAS 477853-82-0)
- Ethyl 3-{[(4-chlorophenyl)carbamoyl]methoxy}pyrido[1,2-a]indole-10-carboxylate (CAS 339107-06-1)
- 4-[(2E)-3-(2,4-Dimethoxyphenyl)prop-2-enoyl]phenyl 4-chlorobenzoate (CAS 331461-54-2)
- Amlodipine Impurity 56 (CAS 2418591-36-1)
- Tetrabutylammonium Acetate (contains 10-15%AcOH) (CAS 10534-59-5)
- 9H-Fluoren-9-yl carbamimidothioate (CAS 64850-99-3)
- 5-Cyclopropoxy-4-(methylthio)picolinaldehyde (CAS 1243466-96-7)
- 3-Oxocyclopent-1-enecarboxylic acid (CAS 108384-36-7)
- 6-Tert-butyl-2-thioxo-2,3-dihydropyrimidin-4(1h)-one (CAS 66698-66-6)
- 3-Bromo-5-methoxybenzaldehyde (CAS 262450-65-7)
- 1,4-Dioxa-9,12-diazadispiro[4.2.5.2]pentadecan-13-one (CAS 1263475-11-1)
- tert-Butyl piperazine-1-carboxylate oxalate (CAS 57260-72-7)
- 1-(Ethoxymethyl)-3,4-dihydroisoquinoline (CAS 88422-90-6)
- Exenatide Acetate (CAS 141732-76-5)
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