Methyl 5-[2-amino-4-(trifluoromethyl)pyrimidin-5-yl]-3-(2-chlorophenyl)-1,2-oxazole-4-carboxylate CAS 338966-60-2
| CAS No. | 338966-60-2 |
| Molecular Formula | C16H10ClF3N4O3 |
| Molecular Weight | 398.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C16H10ClF3N4O3, Methyl 5-[2-amino-4-(trifluoromethyl)pyrimidin-5-yl]-3-(2-chlorophenyl)-1,2-oxazole-4-carboxylate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 398.72 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Methyl 5-[2-amino-4-(trifluoromethyl)pyrimidin-5-yl]-3-(2-chlorophenyl)-1,2-oxazole-4-carboxylate (CAS 338966-60-2), molecular formula C16H10ClF3N4O3 and molecular weight 398.72 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 5-[2-amino-4-(trifluoromethyl)pyrimidin-5-yl]-3-(2-chlorophenyl)-1,2-oxazole-4-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H10ClF3N4O3 |
| Molecular Weight | 398.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Methyl Standards
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- 3-Amino-N-(4-methylthiazol-2-yl)-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide (CAS 626222-24-0)
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Recommended Standards
- CAS 48165-50-0 (CAS 48165-50-0)
- <I>N</I>-(5-chloro-2-pyridyl)bis(trifluoromethanesulfonimide) (CAS 145100-51-2)
- 3,4-Dichloro-N-(5-chloro-2-(4-methylpiperazin-1-yl)phenyl)benzamide (CAS 383146-63-2)
- N1-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-4-(trifluoromethyl)benzene-1,2-diamine (CAS 478262-14-5)
- 4-(2,2-Diethoxy-ethoxy)-but-1-ene (CAS 1343915-25-2)
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- Methyl 3-(2-ethoxy-2-oxoethoxy)-4-nitrobenzoate (CAS 214848-28-9)
- Netupitant Impurity 43 (CAS CATO-C4X-122343)
- 911678-16-5 N-(2-Bromoethyl)-N,N-dimethylprop-2-yn-1-aminium bromide DTXSID00723267 (CAS 911678-16-5)
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