1-[(4-Chlorophenyl)methyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide CAS 338977-32-5
| CAS No. | 338977-32-5 |
| Molecular Formula | C14H10ClF3N2O2 |
| Molecular Weight | 330.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 330.69 g/mol gives 1-[(4-Chlorophenyl)methyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1-[(4-Chlorophenyl)methyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide (CAS 338977-32-5), a certified reference material (molecular formula C14H10ClF3N2O2, MW 330.69 g/mol) for analytical method development and quality control.
The molecular framework of 1-[(4-Chlorophenyl)methyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide (C14H10ClF3N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H10ClF3N2O2 |
| Molecular Weight | 330.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 1-(2-Chlorophenyl)-3-[4-(trifluoromethoxy)phenyl]urea (CAS 406930-04-9)
- 1-(4-Chlorophenyl)-3-(4-(trifluoromethoxy)phenyl)urea (CAS 54730-71-1)
- 1-[(2-Chlorophenyl)methyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide (CAS 400084-97-1)
- 1-[(3-Chlorophenyl)methyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide (CAS 338977-69-8)
- 2-(4-Chlorophenyl)-2-(3-(trifluoromethyl)phenoxy)acetic acid (CAS 4687-08-5)
- 5-[(E)-2-[5-(2-Chlorophenyl)furan-2-yl]ethenyl]-3-methyl-4-nitro-1,2-oxazole (CAS 1164513-00-1)
- 2-((3-(4-Chlorophenyl)-2-oxo-2h-chromen-7-yl)oxy)acetic acid (CAS 141113-52-2)
- N-(4-chlorophenyl)-2-((1,3-dioxoisoindolin-2-yl)oxy)acetamide (CAS 153078-95-6)
Recommended Standards
- 1-[2-chloro-5-(trifluoromethyl)phenyl]-1h,4h,5h,6h-cyclopenta[c]pyrazole-3-carboxylic acid (CAS 926187-51-1)
- 2-Amino-N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)benzohydrazide (CAS 338397-82-3)
- 3-(4-Chloro-2-methylphenoxy)-5-(trifluoromethyl)pyridine-2-carboxamide (CAS 338968-19-7)
- (E)-3-Chloro-N'-hydroxy-N-[(pyridin-3-yl)methyl]-5-(trifluoromethyl)pyridine-2-carboximidamide (CAS 320420-32-4)
- 2-(4-Iodophenoxy)-5-(trifluoromethyl)pyridine (CAS 694449-19-9)
- Methyl 6-chloro-4-methyl-1H-indole-2-carboxylate (CAS 1698700-02-5)
- 2-(5-Amino-3-(furan-2-yl)-1H-pyrazol-1-yl)-3,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one (CAS 1207024-97-2)
- 5-(Ethylsulfonyl)-4-(4-nitrophenyl)-2-thioxo-1,2-dihydropyridine-3-carbonitrile (CAS 1707584-02-8)
- 4-[5-(Benzylsulfanyl)-1,3,4-thiadiazol-2-yl]-2,6-di-tert-butylphenol (CAS 221641-79-8)
- 5-Isobenzofurancarboxylic acid, 1,3-dihydro-1,3-dioxo-, polymer with 1,1'-methylenebis[4-isocyanatobenzene] (CAS 25053-57-0)
- Tert-butyl (2-(4-chlorophenyl)-2-hydroxyethyl)carbamate (CAS 939757-24-1)
- N-(5-Methyl-1,3,4-thiadiazol-2-yl)-2-(piperazin-1-yl)acetamide (CAS 141400-72-8)
- Bithionol (CAS 97-18-7)
- Eosinophilotactic Peptide (CAS 61756-28-3)
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