Isavuconazole Impurity N14 CAS 338990-63-9
| CAS No. | 338990-63-9 |
| Molecular Formula | C40H43F2N8O7S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Isavuconazole Impurity N14 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Isavuconazole Impurity N14 (CAS 338990-63-9, C40H43F2N8O7SCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Isavuconazole Impurity N14 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 853.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C40H43F2N8O7S Cl |
| Molecular Weight | 853.34 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 1 |
Related Isavuconazole Standards
- Isavuconazole Impurity 221 (CAS 1062201-83-5)
- Isavuconazole HCl (CAS 1121545-23-0)
- Isavuconazole Impurity 24 (CAS 1176988-44-5)
- Isavuconazole Impurity 33 (CAS 1180002-01-0)
- Isavuconazole Impurity 60 (CAS 123-73-9)
- Isavuconazole Impurity 62 (CAS 1286730-05-9)
- Isavuconazole-d4 (CAS 1346598-58-0)
- Isavuconazole Impurity N15 (CAS 1443-80-7)
Recommended Standards
- Bambuterol EP Impurity F (CAS 112935-94-1)
- Lamivudine Impurity 23 (CAS CATO-C4X-119423)
- Eszopiclone impurity 28 Sodium salt (CAS CATO-C4X-123828)
- 3-methyl-1H-pyrrolo[3,2-c]pyridine (CAS 22930-75-2)
- 2,4,6-triethyl 1,3,5-triazine-2,4,6-tricarboxylate 898-22-6 Z234855724 (CAS 898-22-6)
- 7-Hydroxy-2,8-dimethyl-3-(o-tolyl)-4h-chromen-4-one (CAS 315233-70-6)
- 7-[4-(Morpholine-4-sulfonyl)phenoxy]-2,4-bis(trifluoromethyl)-1,8-naphthyridine (CAS 338412-25-2)
- (R)-(4-bromophenyl)(3-hydroxypyrrolidin-1-yl)methanone (CAS 924643-26-5)
- 6-Bromo-7-chloro-1(2H)-isoquinolinone (CAS 1036712-57-8)
- Ac, Gastrin Releasing Peptide (20-27), porcine (CAS 77714-20-6)
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