N-benzyl-5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridine-3-carboxamide CAS 339020-73-4
| CAS No. | 339020-73-4 |
| Molecular Formula | C21H13F3N2O3 |
| Molecular Weight | 398.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-benzyl-5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridine-3-carboxamide.
N-benzyl-5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridine-3-carboxamide (CAS 339020-73-4), molecular formula C21H13F3N2O3 and molecular weight 398.33 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, N-benzyl-5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridine-3-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 398.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H13F3N2O3 |
| Molecular Weight | 398.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Ethyl 2-(4-{[2-nitro-4-(trifluoromethyl)phenyl]amino}phenoxy)propanoate (CAS 73553-87-4)
- Losartan Impurity 46 (CAS 757149-84-1)
- Bis(2,4-dinitrophenyl) disulfide (CAS 2217-55-2)
- Etofenamate Impurity 2 (CAS CATO-C4X-26032)
- 3-{4-chloro-5,6-dimethylthieno[2,3-d]pyrimidin-2-yl}pyridine (CAS 742094-64-0)
- 3,5-Dichlorophenylhydrazine hydrochloride 1-(3,5-dichlorophenyl)hydrazine hydrochloride 3,5-dichlorophenylhydrazine hcl 63352-99-8 (CAS 63352-99-8)
- 3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)-N-(2-hydroxyethoxy)-5-((3-oxo-1,2-oxazinan-2-yl)methyl)benzamide (CAS 874101-00-5)
- 2-(1-(tert-Butoxycarbonyl)pyrrolidin-2-yl)thiazole-4-carboxylic acid (CAS 1824349-18-9)
- 4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-amine (CAS 189575-70-0)
- 3-{[(3-chlorophenyl)methyl]amino}propanoic acid hydrochloride (CAS 1172342-74-3)
- Benzyl 4-(iodomethyl)piperidine-1-carboxylate (CAS 149897-41-6)
- 1-(4-(2-Fluorophenyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 955975-49-2)
- 3-Bromo-5-(tert-butoxy)-4-cyclopropoxypyridine (CAS 1243285-62-2)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
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