2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(2-fluorophenyl)-2-(morpholin-4-yl)acetonitrile CAS 339097-07-3

Purity 97%+In StockPharmaceutical Standards
CAS No.339097-07-3
Molecular FormulaC18H14ClF4N3O
Molecular Weight399.77 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(2-fluorophenyl)-2-(morpholin-4-yl)acetonitrile CAS 339097-07-3 chemical structure

Description

CATO supplies 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(2-fluorophenyl)-2-(morpholin-4-yl)acetonitrile (CAS 339097-07-3), a certified reference material (molecular formula C18H14ClF4N3O, MW 399.77 g/mol) for analytical method development and quality control.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(2-fluorophenyl)-2-(morpholin-4-yl)acetonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 399.77 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(2-fluorophenyl)-2-(morpholin-4-yl)acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H14ClF4N3O
Molecular Weight399.77 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms3

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