3397-30-6 N-(2,2,2-Trifluoroacetyl)glycine 2,5-Dioxo-1-pyrrolidinyl Ester N-Trifluoroacetylglycine N-Succinimidyl Ester N-[2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-2,2,2-trifluoroacetamide N-[[N-(Trifluoroacetyl)glycyl]oxy]succinimide CAS 3397-30-6

Purity 97%+In StockPharmaceutical Standards
CAS No.3397-30-6
Molecular FormulaC8H7F3N2O5
Molecular Weight268.15 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3397-30-6 N-(2,2,2-Trifluoroacetyl)glycine 2,5-Dioxo-1-pyrrolidinyl Ester N-Trifluoroacetylglycine N-Succinimidyl Ester N-[2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-2,2,2-trifluoroacetamide N-[[N-(Trifluoroacetyl)glycyl]oxy]succinimide CAS 3397-30-6 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3397-30-6 N-(2,2,2-Trifluoroacetyl)glycine 2,5-Dioxo-1-pyrrolidinyl Ester N-Trifluoroacetylglycine N-Succinimidyl Ester N-[2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-2,2,2-trifluoroacetamide N-[[N-(Trifluoroacetyl)glycyl]oxy]succinimide.

3397-30-6 N-(2,2,2-Trifluoroacetyl)glycine 2,5-Dioxo-1-pyrrolidinyl Ester N-Trifluoroacetylglycine N-Succinimidyl Ester N-[2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-2,2,2-trifluoroacetamide N-[[N-(Trifluoroacetyl)glycyl]oxy]succinimide (CAS 3397-30-6), molecular formula C8H7F3N2O5 and molecular weight 268.15 g/mol, is a CATO reference standard with documented purity and traceability.

3397-30-6 N-(2,2,2-Trifluoroacetyl)glycine 2,5-Dioxo-1-pyrrolidinyl Ester N-Trifluoroacetylglycine N-Succinimidyl Ester N-[2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-2,2,2-trifluoroacetamide N-[[N-(Trifluoroacetyl)glycyl]oxy]succinimide (C8H7F3N2O5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H7F3N2O5
Molecular Weight268.15 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF-containing
Nitrogen Atoms2

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