2-([1,1'-Biphenyl]-2-yloxy)-5-(trifluoromethyl)aniline CAS 340018-76-0
| CAS No. | 340018-76-0 |
| Molecular Formula | C19H14F3NO |
| Molecular Weight | 329.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-([1,1'-Biphenyl]-2-yloxy)-5-(trifluoromethyl)aniline (CAS 340018-76-0) is a high-purity analytical reference standard with the molecular formula C19H14F3NO and a molecular weight of 329.32 g/mol.
2-([1,1'-Biphenyl]-2-yloxy)-5-(trifluoromethyl)aniline (C19H14F3NO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 2-([1,1'-Biphenyl]-2-yloxy)-5-(trifluoromethyl)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H14F3NO |
| Molecular Weight | 329.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Biphenyl Standards
- 4-([1,1-Biphenyl]-4-yloxy)-2-(trifluoromethyl)-phenylamine (CAS 10141-35-2)
- 2-([1,1'-Biphenyl]-4-yloxy)-5-(trifluoromethyl)aniline (CAS 904253-69-6)
- 4-([1,1-Biphenyl]-2-yloxy)-2-(trifluoromethyl)-phenylamine (CAS 946698-03-9)
- 4-([1,1-Biphenyl]-2-yloxy)-3-(trifluoromethyl)-phenylamine (CAS 946662-77-7)
- 4-([1,1-Biphenyl]-4-yloxy)-3-(trifluoromethyl)-phenylamine (CAS 946697-73-0)
- (2E)-1-{[1,1'-Biphenyl]-4-yl}-3-(3-nitrophenyl)prop-2-en-1-one (CAS 1042167-64-5)
- 6-([1,1'-Biphenyl]-3-yl)-2-hydroxyisoquinoline-1,3(2H,4H)-dione (CAS 1354742-79-2)
- 2-([1,1'-Biphenyl]-4-ylmethoxy)isoindoline-1,3-dione (CAS 1885-53-6)
Recommended Standards
- 1-(Naphthalen-2-yl)-3-((2,3,4-trifluorophenyl)amino)propan-1-one (CAS 868255-61-2)
- 1-(4-((4-Fluorobenzyl)oxy)phenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 676479-42-8)
- 3-(Thiophen-2-yl)-6-(trifluoromethyl)thieno[3,2-b]pyridine-2-carboxylic acid (CAS 478080-13-6)
- N-(2-(3-aminopiperidin-1-yl)-2-oxoethyl)-4-(trifluoromethyl)benzamide (CAS 1839700-01-4)
- 1-(3,4-Dimethylphenyl)-4,5,6,7-tetrahydro-1H-indazol-4-amine (CAS 1228551-83-4)
- 6-(Difluoromethoxy)pyridine-3-carbonitrile (CAS 1198103-42-2)
- 2-Amino-4-methylpyrimidine-5-boronic acid pinacol ester, 97% (CAS 944401-55-2)
- 4-(4-Fluorobenzoyl)piperidine Hydrochloride (CAS 25519-78-2)
- 4-Bromo-5H-pyrrolo[2,3-d]pyrimidine (CAS 1194755-67-3)
- 5-(2,4-dichlorophenyl)-4-isopropyl-4H-1,2,4-triazole-3-thiol (CAS 91193-84-9)
- N-[(2,4-difluorophenyl)methyl]cyclopropanamine (CAS 926244-58-8)
- 2-([1,1'-Biphenyl]-4-yl)malonaldehyde (CAS 125507-91-7)
- 5-chloro-4-methoxy-2-methylbenzene-1-sulfonyl chloride (CAS 1368747-92-5)
- Semaglutide (CAS 910463-68-2（free base）)
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