3-(3-(Trifluoromethoxy)phenoxy)propanoic acid CAS 340825-27-6
| CAS No. | 340825-27-6 |
| Molecular Formula | C10H9F3O4 |
| Molecular Weight | 250.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-(3-(Trifluoromethoxy)phenoxy)propanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-(3-(Trifluoromethoxy)phenoxy)propanoic acid (CAS 340825-27-6) is a high-purity analytical reference standard with the molecular formula C10H9F3O4 and a molecular weight of 250.17 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 3-(3-(Trifluoromethoxy)phenoxy)propanoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 250.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H9F3O4 |
| Molecular Weight | 250.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Trifluoromethoxy Standards
- Methyl 2-[4-(trifluoromethoxy)phenoxy]acetate (CAS 1403316-31-3)
- 2-(4-(Trifluoromethoxy)phenoxy)propanoic acid (CAS 175204-35-0)
- 2-(4-(Trifluoromethoxy)phenoxy)acetohydrazide (CAS 175204-36-1)
- 3-(2-(Trifluoromethoxy)phenoxy)propanoic acid (CAS 276697-78-0)
- 3-(4-(Trifluoromethoxy)phenoxy)propanoic acid (CAS 874774-55-7)
- 2-(Trifluoromethoxy)terephthalic acid (CAS 175278-21-4)
- {[4-(trifluoromethoxy)phenyl]methyl}thiourea (CAS 296277-22-0)
- 3-[4-(Trifluoromethoxy)phenyl]acryloyl chloride (CAS 306936-02-7)
Recommended Standards
- 2-Methyl-5,7-dinitroquinazolin-4(3H)-one (CAS 890092-86-1)
- 3,3,3-Trifluoro-2-hydroxy-2-(4-methoxyphenyl)propionic acid (CAS 502607-25-2)
- 2-Methoxymethoxy-5-(trifluoromethyl)benzoic acid (CAS 368422-27-9)
- 3-Trifluoromethyl-4-hydroxy-5-methoxy Methyl Benzoate (CAS 883241-39-2)
- S-Ethyl 2-(5-ethoxytetrahydrofuran-2-yl)ethanethioate (CAS 475275-15-1)
- 2-Amino-5-[(furan-2-yl)methyl]-5-(thiophen-2-yl)-4,5-dihydro-1H-imidazol-4-one (CAS 1354917-71-7)
- cis-4-(Aminomethyl)piperidin-3-ol dihydrochloride (CAS 2007924-95-8)
- 3-(2-CHLORO-4-HYDROXYPHENYL)PROPIONIC ACID (CAS 1261449-78-8)
- Palbociclib Impurity 102 (CAS CATO-C4X-1125102)
- 2-[5-(bromomethyl)-2-methyl-pyrazol-3-yl]acetonitrile (CAS 2853613-31-5)
- 4-(Chloromethyl)-2-(1,3-dioxolan-2-yl)pyridine (CAS 1256824-16-4)
- (3aR,4S,7R,7aS,8S)-8-((1,10-Phenanthrolin-4-yl)ethynyl)octahydro-1H-4,7-methanoisoindol-1-one (CAS 2416567-38-7)
- 4-(Benzofuran-2-yl)phenol (CAS 26870-36-0)
- Semaglutide Impurity 128 (CAS 2490269-78-6)
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